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Vanillylacetone(CAS#122-48-5)

Chemical Property:

Molecular Formula C11H14O3
Molar Mass 194.23
Density 1.14g/mLat 25°C(lit.)
Melting Point 40-41°C(lit.)
Boling Point 141°C0.5mm Hg(lit.)
Flash Point >230°F
JECFA Number 730
Solubility Soluble in ether and dilute alkali, slightly soluble in water and petroleum ether.
Vapor Presure 0.000143mmHg at 25°C
Appearance Crystals (from acetone, petroleum ether, ether-petroleum ether)
Color White to Pale Yellow Low-Melting
Merck 14,10166
pKa 10.03±0.20(Predicted)
Storage Condition Sealed in dry,2-8°C
Refractive Index n20/D 1.541(lit.)
MDL MFCD00048232
In vitro study Vanillylacetone is similar in chemical structure to other fragrance chemicals such as vanillin and eugenol. It is used as a flavoring additive in sesame oils and fragrances to introduce a spice flavor. Ginger does not contain vanillylacetone; Ginger is converted to gingerol by cooking, which is the current example of conversion to vanillylacetone by an aldol condensation reaction. Vanillylacetone may be the active ingredient of ginger to exert antidiarrheal effect.

Product Detail

Product Tags

Risk Codes 36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 – Wear suitable protective clothing.
WGK Germany 2
RTECS EL8900000
TSCA Yes
HS Code 29333999

 

Introduction

4-4-Hydroxy-3-methoxybutyl-2-one, also known as 4-hydroxy-3-methoxypentanone, is an organic compound. The following is an introduction to some of its properties, uses, manufacturing methods and safety information:

 

Quality:

- Appearance: Colorless or light yellow liquid or solid.

- Solubility: Soluble in organic solvents such as ethanol and dimethylformamide, insoluble in water.

- Toxicity: The compound is toxic and requires necessary safety measures when inhaled or in contact with the skin.

 

Use:

- Chemistry experiments: It can also be used as a reagent for certain chemistry experiments.

 

Method:

The preparation method of 4-4-hydroxy-3-methoxybutyl-2-one can be achieved by organic synthesis under appropriate conditions. There may be several ways to prepare it, but here is one of the possible methods:

Dissolve an appropriate amount of pentanone in an organic solvent.

Add excess sodium hydroxide solution.

At a constant temperature and pressure, methanol is slowly added dropwise into the reaction mixture.

With the addition of methanol, 4-4-hydroxy-3-methoxybutyl-2-one is formed in the reaction mixture.

The product is further processed and purified to obtain the final compound.

 

Safety Information:

- This compound is somewhat toxic and should be avoided by direct inhalation or skin contact.

- Appropriate safety measures must be taken when in use, such as wearing chemical goggles, wearing chemical gloves and protective clothing.

- Waste disposal: Waste is mixed with suitable solvents and disposed of by a qualified waste disposal facility in accordance with local regulations.

 


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