Urea, N-[[(6'R)-6',7'-dihydro-6'-hydroxy-2',4',6'-trimethyl-7'-oxospiro[cyclopropane-1,5'-[5H]inden]-3′-yl]methyl]-N-hydroxy(CAS#924835-67-6)
Urea, N-[[(6'R)-6',7'-dihydro-6'-hydroxy-2',4',6'-trimethyl-7'-oxospiro[cyclopropane-1,5'-[5H]inden]-3′-yl]methyl]-N-hydroxy(CAS#924835-67-6)
Mechanism: LP-184 is an acylfluoroethylene analogue with potent anticancer activity in ovarian, colon, prostate and pancreatic cell lines, capable of inhibiting tumor growth.
Synthesis method: The synthesis of LP-184 usually involves multi-step organic reactions, and the starting material is usually a compound with a spiro-ring structure, which undergoes a series of reactions such as hydroxyl protection, methylation, and cyclopropanation, and finally introduces functional groups such as urea and hydroxyl groups to obtain the target product. The exact synthetic route will vary depending on laboratory conditions and the choice of starting material.
Physical and chemical properties: At present, there is little data on its specific physical and chemical properties in public information. However, it can be speculated that due to the structure of hydroxyl group, carbonyl group and spirocyclic ring in the molecule, it may have a certain polarity, and its solubility in organic solvents may be good, while its solubility in water is relatively limited. There is no public information on its melting point, boiling point and other data.