Tosylmethyl isocyanide（CAS# 36635-61-7)
| Risk Codes | 23/24/25 – Toxic by inhalation, in contact with skin and if swallowed. |
| Safety Description | S36/37 – Wear suitable protective clothing and gloves. S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S38 – In case of insufficient ventilation, wear suitable respiratory equipment. S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. S28A - |
| UN IDs | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 21 |
| HS Code | 29299000 |
| Hazard Note | Irritant |
| Hazard Class | 6.1(b) |
| Packing Group | III |
Introduction
Methyl isothiocyanate is an organic compound. It is a colorless liquid with a strong spicy smell at room temperature. The following is an introduction to some basic properties, uses, preparation methods and safety information of methylsulfonylmethylisoisonitrile:
Quality:
Appearance: Colorless liquid
Smell: Has a strong spicy smell
Density: about 1.08 g/cm3
Ignition Point: Approximately 48°C
Solubility: Soluble in many organic solvents, such as alcohols, ethers and ketones
Use:
Pesticides: Methylsulfonylmethylisonitrile can be used as an insecticide for pest control in farmland.
Biological research: Methylsulfonylmethylisosinitrile can be used in biological research, for example in the labeling and detection of proteins.
Method:
Methylsulfonylmethylisonitrile is usually prepared by:
Preparation from isothiocyanate: Isothiocyanate is reacted with an appropriate methylation reagent (e.g., methyl bromide) to generate methylsulfonylmethylisonitrile.
Preparation from methyl thionofolate: methyl thionofolate is reacted with a base to form methyl isonitrile, which is then reacted with nitrous acid to obtain methylsulfonylmethylisonitrile.
Safety Information:
Methylsulfonyl methylisonitrile has a pungent odor and strong irritation. Contact with skin, eyes, or inhalation may cause irritation and burns.
Appropriate precautions such as protective eyewear, gloves and masks must be taken when using or handling methylsulfonyl methylisonitrile.
Methylsulfonylmethylisonitrile has high volatility and should be kept away from open flames and high temperatures when stored and used to avoid fire and explosion hazards.
When handling methylsulfonylmethylisonitrile, proper operating procedures should be followed and adequate ventilation conditions should be ensured. It should not be exposed to an unlicensed environment under any circumstances.
