Tosyl chloride(CAS#98-59-9)
Risk Codes | R34 – Causes burns R29 – Contact with water liberates toxic gas R41 – Risk of serious damage to eyes R38 – Irritating to the skin |
Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S27 – Take off immediately all contaminated clothing. S39 – Wear eye / face protection. |
UN IDs | UN 3261 8/PG 2 |
WGK Germany | 1 |
RTECS | DB8929000 |
FLUKA BRAND F CODES | 9-21 |
TSCA | Yes |
HS Code | 29049020 |
Hazard Note | Corrosive |
Hazard Class | 8 |
Packing Group | II |
Toxicity | LD50 orally in Rabbit: 4680 mg/kg |
Introduction
4-Toluenesulfonyl chloride is an organic compound. The following is an introduction to its nature, use, preparation method and safety information:
Quality:
- 4-Toluenesulfonyl chloride is a colorless to yellowish liquid with a pungent odor at room temperature.
- It is an organic acid chloride that reacts quickly with some nucleophiles such as water, alcohols, and amines.
Use:
- 4-Toluenesulfonyl chloride is often used as a reagent in organic synthesis for the synthesis of acyl compounds and sulfonyl compounds.
Method:
- The preparation of 4-toluenesulfonyl chloride is usually obtained by the reaction of 4-toluenesulfonic acid and sulfuryl chloride. The reaction is usually carried out at a lower temperature, such as under cooling conditions.
Safety Information:
- 4-Toluenesulfonyl chloride is an organic chloride compound that is a harsh chemical. When using, care should be taken to safe operation and avoid direct contact with the skin or inhalation of gases.
- Operate under well-ventilated laboratory conditions and be equipped with appropriate personal protective equipment such as gloves, safety goggles, and face shields.
- Inhalation or accidental ingestion may cause respiratory irritation, redness, swelling and pain. In the event of contact or accident, rinse the skin immediately with plenty of water and, if necessary, consult a doctor.