Thiazol-2-yl-acetic acid（CAS# 188937-16-8)
Risk and Safety
| Hazard Symbols | Xi – Irritant |
| Risk Codes | 36 – Irritating to the eyes |
| Safety Description | 26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
Thiazol-2-yl-acetic acid（CAS# 188937-16-8) introduction
2-thiazoleacetic acid is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of 2-thiazoleacetic acid:
Quality:
- Appearance: Light yellow to white crystalline powder
- Solubility: Soluble in ethanol, ether and chloroform, insoluble in water
Use:
- 2-Thiazoleacetic acid can be used as an intermediate in the synthesis of bioactive compounds.
Method:
The preparation method of 2-thiazoleacetic acid includes the following steps:
2-thiazole ethylamine is synthesized first, which can be obtained by the reaction of thiazole and chloroethanol under alkaline conditions.
2-thiazolethylamine is acylated under acidic conditions and reacted with an acylating agent such as acetic anhydride to generate 2-thiazoleacetic acid.
Safety Information:
- 2-thiazoleacetic acid should be avoided from contact with the skin and eyes, and inhalation should be avoided.
- Appropriate protective equipment, such as gloves and protective eyewear, should be worn when operating.
- Store away from high temperatures, ignitions, and oxidants.
- In case of accidental ingestion or skin contact, wash the affected area immediately and seek medical assistance.
