Tetraphenylphosphonium bromide（CAS# 2751-90-8)
| Hazard Symbols | Xi – Irritant |
| Risk Codes | 36/37/38 – Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 – Wear suitable protective clothing. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10 |
| TSCA | Yes |
| HS Code | 29310095 |
Introduction
Tetraphenylphosphine bromide is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of tetraphenylphosphine bromide:
Quality:
- Tetraphenylphosphine bromide is a colorless crystal or white powdery solid.
- Soluble in organic solvents such as ethers and chlorinated hydrocarbons, insoluble in water.
- It is a strong Lewis base that can form complexes with many metals.
Use:
- Tetraphenylphosphine bromide is widely used as a chemical reagent in organic synthesis.
- It can be used as a transition metal ligand and is involved in catalytic reactions.
- It is commonly used in organic synthesis for the addition of carbonyl compounds and carboxylic acids, as well as for the amination reaction and conjugate addition of olefins.
Method:
- Tetraphenylphosphine bromide can be prepared by reacting tetraphenylphosphine with hydrogen bromide.
- Usually reacts in organic solvents such as ether or toluene.
- The resulting tetraphenylphosphine bromide can be further crystallized to produce a pure product.
Safety Information:
- Tetraphenylphosphine bromide is irritating to the skin and eyes and should be avoided in direct contact.
- Use in a well-ventilated area and wear appropriate personal protective equipment such as gloves and glasses.
- Be aware that it may produce toxic fumes and corrosive gases when heated and decomposed.
- When storing, it should be kept away from fire and oxidants, and avoid contact with oxygen.
- If ingested or inhaled, seek medical attention immediately.
