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tert-Butyl 3-oxoazetidine-1-carboxylate(CAS# 398489-26-4)

Chemical Property:

Molecular Formula C8H13NO3
Molar Mass 171.19
Density 1.174±0.06 g/cm3(Predicted)
Melting Point 47-51 °C
Boling Point 251.3±33.0 °C(Predicted)
Flash Point 102°C
Vapor Presure 0.0369mmHg at 25°C
Appearance Crystal Powder
Color White to off-white
pKa -1.99±0.20(Predicted)
Storage Condition Inert atmosphere,2-8°C
Sensitive Moisture Sensitive/Stench
MDL MFCD01861741

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Risk and Safety

Risk Codes R22 – Harmful if swallowed
R37/38 – Irritating to respiratory system and skin.
R41 – Risk of serious damage to eyes
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39 – Wear eye / face protection.
UN IDs UN 3335
WGK Germany 3
HS Code 29339900
Hazard Class IRRITANT

tert-Butyl 3-oxoazetidine-1-carboxylate(CAS# 398489-26-4) Introduction
1-BOC-3-azetidinone is an organic compound, also known as 1-BOC-azetidin-3-one. Its chemical structure contains an azetidinone ring and a protecting group attached to the nitrogen, called BOC (tert-butoxycarbonyl).

Properties of the compound:
- Appearance: Commonly a white solid
- Solubility: Soluble in some organic solvents, such as chloroform, dimethylformamide, etc.
- Protective group: The BOC group is a temporary protective group that can be used to protect the amine group during the synthesis process to prevent it from undergoing other reactions

Uses of 1-BOC-3-azetidinone:
- Synthetic intermediate: As an organic synthesis intermediate, it is often used to synthesize other organic compounds
- Biological activity research: It can be used to explore or study the biological activity mechanism of molecules

Preparation of 1-BOC-3-azetidinone:
1-BOC-3-azetidinone can be prepared by a variety of synthetic methods. One of the commonly used methods is to obtain 1-BOC-3-azetidinone by reacting succinic anhydride and dimethylformamide.

Safety information:
- This compound may be irritating to the skin, eyes and mucous membranes, and direct contact should be avoided when in contact.
- When operating, appropriate personal protective equipment should be worn, such as laboratory gloves, goggles, etc.
- It should be handled in a well-ventilated area and avoid prolonged exposure to its vapor or gas.
- It should be stored properly, away from ignition sources and flammable substances such as oxidants.


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