S-4-Chloro-alpha-methylbenzyl alcohol CAS 99528-42-4
Risk and Safety
| Hazard Symbols | Xn – Harmful |
| Risk Codes | R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 – Irritating to eyes, respiratory system and skin. |
| Safety Description | 26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
99528-42-4 - Nature
| specific rotation | -48 ° (C=1 IN CHLOROFORM) |
| optical activity (optical activity) | [α]20/D -48.0°, c = 1 in chloroform |
99528-42-4 - Reference Information
| use | (S)-1-(4-chlorophenyl) ethanol is the basic raw material for the synthesis of a new type of N,N’-dimethylpiperazine with metal binding ability. |
Brief introduction
(S)-1-(4-chlorophenyl)ethanol is an organic compound. It is a chiral molecule with an extended chiral ring-like structure. The following is an introduction to the properties, uses, preparation methods and safety information of this compound:
Quality:
- Appearance: (S)-1-(4-chlorophenyl)ethanol is a colorless to light yellow liquid.
- Soluble: It can be soluble in many organic solvents, such as alcohols, ethers and aromatic hydrocarbons.
Use:
- (S)-1-(4-chlorophenyl)ethanol is commonly used as an intermediate in organic synthesis.
- It can also be used in the preparation of chiral compounds, chiral ligands, and chiral catalysts, among others.
Method:
- (S)-1-(4-chlorophenyl)ethanol can be synthesized by the following steps:
1. Ethylene acetonitrile is condensed with 4-chlorobenzaldehyde to form N-[(4-chlorobenzene)methyl]ethyleneacetonitrile.
2. This intermediate is then heated with sodium hydroxide and ethanol to produce (S)-1-(4-chlorophenyl)ethanol.
Safety Information:
- (S)-1-(4-chlorophenyl)ethanol is generally relatively safe under normal operating conditions, but there are still some basic laboratory safety operating procedures that need to be followed.
- It can be an irritant of the eyes, skin, and respiratory tract and must be avoided from direct contact and inhalation. Appropriate personal protective equipment such as gloves, protective glasses, and masks should be worn during handling.
- When handling or storing the compound, care should be taken to avoid ignition and high temperatures.
- When using and disposing of, refer to the relevant Safety Data Sheets and chemical labels, and follow operational guidelines to ensure safety and health risks are minimized.
