(R)-N-BOC-3-Aminobutyric acid ethyl ester(CAS# 159877-47-1)
(R)-N-BOC-3-Aminobutyric acid ethyl ester(CAS# 159877-47-1) introduction
Methyl BOC-R-3-aminobutyrate is an organic compound. It is a white solid with a peculiar odor. The following is an introduction to the properties, uses, preparation methods and safety information of BOC-R-3-aminobutyrate:
Quality:
- Appearance: White solid
- Solubility: Soluble in organic solvents such as methanol and methylene chloride
Uses: It can be used as a protective group in protein synthesis to prevent non-specific reactions from occurring. It can also be used to synthesize other organic compounds, such as amino acids and peptides.
Method:
Methyl BOC-R-3-aminobutyric acid is usually synthesized by the following steps:
Acrylonitrile is reacted with triethylamine to obtain aminoacrylate triethylamine salt.
Aminoacrylate triethylamine salt is reacted with formic acid to obtain methyl(R)-N-Boc-3-aminoacrylic acid.
Methyl(R)-N-Boc-3-aminoacrylic acid is reacted with methanol to form methyl BOC-R-3-aminobutyrate.
Safety Information:
- Wear appropriate personal protective equipment, such as protective eyewear and gloves.
- Avoid inhalation or contact with skin and eyes.
- When storing and handling, keep away from fire sources and high temperature environments, and ensure a well-ventilated working environment.
- Operate in accordance with chemical-related safety norms and regulations.