(R)-1-Boc-3-hydroxypiperidine(CAS#143900-43-0)
Hazard Symbols | T – Toxic |
Risk Codes | R36/37/38 – Irritating to eyes, respiratory system and skin. R41 – Risk of serious damage to eyes R37/38 – Irritating to respiratory system and skin. R25 – Toxic if swallowed |
Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
UN IDs | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
HS Code | 29333990 |
Hazard Class | 6.1 |
Packing Group | Ⅲ |
Introduction
(R)-1-Boc-3-hydroxypiperidine, chemically known as (R)-1-(tert-butoxycarbonyl)-3-hydroxypiperidine, is an organic compound. It is a solid and chemically stable. The compound has a stereocenter, exhibits optical rotation, and has a (R)-stereoconfiguration.(R)-1-Boc-3-hydroxypiperidine is widely used in organic synthesis. It can participate in esterification, etherification, amination and other reactions, and synthesize compounds with specific biological activities by adjusting other functional groups.Preparation of (R)-1-Boc-3-hydroxypiperidine is usually done by a two-step reaction. Hydroxypiperidine is reacted with tert-butyl carbonate to obtain 1-Boc-3-hydroxypiperidine. Subsequently, by stereoselective reduction, (R)-1-Boc-3-hydroxypiperidine was obtained.It is a combustible item and should be stored in a cool, dry, well-ventilated place. During operation, protective gloves and eye protection should be worn. Avoid contact with strong oxidants, strong acids and other substances to avoid dangerous reactions.