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Quinolin-5-ol(CAS# 578-67-6)

Chemical Property:

Molecular Formula C9H7NO
Molar Mass 145.16
Density 1.1555 (rough estimate)
Melting Point 223-226°C(lit.)
Boling Point 264.27°C (rough estimate)
Flash Point 143.07°C
Water Solubility 416.5mg/L(20 ºC)
Solubility DMSO, Methanol
Vapor Presure 0mmHg at 25°C
Appearance Solid
Color Colorless to yellow, may darken during storage
BRN 114514
pKa pK1:5.20(+1);pK2:8.54(0) (20°C)
Storage Condition Keep in dark place,Inert atmosphere,Room temperature
Refractive Index 1.4500 (estimate)
MDL MFCD00006792

Product Detail

Product Tags

Hazard Symbols Xi – Irritant
Risk Codes 36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 – Wear suitable protective clothing.
WGK Germany 3
RTECS VC4100000
HS Code 29334900
Hazard Note Irritant

 

Introduction

5-Hydroxyquinoline, also known as 5-hydroxyquinoline, is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of 5-hydroxyquinoline:

 

Quality:

Appearance: 5-Hydroxyquinoline is a colorless crystalline solid.

Solubility: It has low solubility in water and is soluble in organic solvents such as ethanol, acetone, and dimethylformamide.

Stability: It is relatively stable at room temperature, but in the presence of strong acids or bases, reactions may occur.

 

Use:

Chemical reagents: 5-hydroxyquinoline can be used as a chemical reagent to play the role of a catalyst in organic synthesis.

Organic synthesis: 5-hydroxyquinoline can be used as an intermediate to participate in the synthesis of other organic compounds.

 

Method:

5-Hydroxyquinoline can be prepared by reacting quinoline with hydrogen peroxide. The specific preparation method is as follows:

Hydrogen peroxide (H2O2) is slowly added to the quinoline solution.

At a lower temperature (usually 0-10 degrees Celsius), the reaction proceeds for a period of time.

5-hydroxyquinoline is formed during the process, which can be filtered, washed, and dried to obtain the final product.

 

Safety Information:

5-Hydroxyquinoline generally does not have significant toxicity to humans under conventional use conditions, but it is still necessary to operate with caution to avoid direct contact with the skin, eyes or inhalation of its dust.

Appropriate personal protective equipment such as laboratory gloves, safety glasses, etc., should be worn during preparation or handling.

When storing and handling, it should be kept away from ignition and oxidants.

When a leak is encountered, appropriate measures should be taken to clean it up and dispose of it.

 


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