pyrimidine-2-carboxylic acid(CAS#31519-62-7)
| Hazard Symbols | Xi – Irritant |
| Risk Codes | 36/37/38 – Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| HS Code | 29335990 |
| Hazard Class | IRRITANT |
Introduction
pyrimidine-2-carboxylic acid is an organic compound with the chemical formula cwww.tianyancha.com H, n₂ O.
Nature:
-Appearance: pyrimidine-2-carboxylic acid is white crystal or crystalline powder.
-Melting point: About 180-185°C.
-Solubility: pyrimidine-2-carboxylic acid has low solubility in water, and its solubility is better in other polar solvents.
Use:
-Chemical synthesis: pyrimidine-2-carboxylic acid is an important intermediate for the synthesis of other organic compounds, and is often used to prepare more complex pyrimidine derivatives.
-Drugs: pyrimidine-2-carboxylic acid has the potential to be used as a precursor for antiviral, antineoplastic and antibacterial drugs.
Method:
pyrimidine-2-carboxylic acid can be prepared by the following steps:
1.2-pyrimidine reacts with chloroacetic acid to generate pyrimidine-2-carboxylic acid chloromethyl ester.
2. pyrimidine-2-carboxylic acid chloromethyl Ester reacts with water to generate pyrimidine-2-carboxylic acid.
Safety Information:
pyrimidine-2-carboxylic acid is generally a relatively safe compound under normal conditions of use. But as a chemical, it can still present a number of safety risks, including:
-Irritating to skin and eyes, so care should be taken to avoid contact with eyes and skin during use.
-During operation, care should be taken to avoid inhaling dust or solution gas.
-Should be properly stored, away from fire and oxidizing agents.
-Follow proper laboratory safety procedures for use and disposal. It is best to check the safety data sheet of the chemical before use to obtain more detailed and accurate safety information.
