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Propofol(CAS# 2078-54-8)

Chemical Property:

Molecular Formula C12H18O
Molar Mass 178.27
Density 0.962 g/mL at 25 °C (lit.)
Melting Point 18 °C (lit.)
Boling Point 256 °C/764 mmHg (lit.)
Flash Point >230°F
Water Solubility Very slightly soluble in water.
Solubility Sensitive to air
Vapor Presure 5.6 mm Hg ( 100 °C)
Appearance Transparent liquid
Color Pale Yellow to Yellow
Merck 14,7834
BRN 1866484
pKa pKa 11.10(H2O,t =20)(Approximate)
Storage Condition 2-8°C

Product Detail

Product Tags

Risk and Safety

Risk Codes R22 – Harmful if swallowed
R36/37/38 – Irritating to eyes, respiratory system and skin.
R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed.
R39/23/24/25 -
R23/24/25 – Toxic by inhalation, in contact with skin and if swallowed.
R11 – Highly Flammable
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S37/39 – Wear suitable gloves and eye/face protection
S36 – Wear suitable protective clothing.
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37 – Wear suitable protective clothing and gloves.
S16 – Keep away from sources of ignition.
S7 – Keep container tightly closed.
UN IDs 2810
WGK Germany 3
RTECS SL0810000
TSCA Yes
HS Code 29089990
Hazard Class 6.1(b)
Packing Group III

 

 

Propofol(CAS# 2078-54-8) Information

quality
Colorless to light yellow liquid with a peculiar odor. Soluble in most organic solvents, insoluble in water.

Method
Propofol can be obtained by using isobutylene as raw material and catalyzed by triphenoxy aluminum to alkylation of phenol.

use
Developed by Stuart and listed in the UK in 1986. It is a short-acting intravenous general anesthetic, and the anesthetic effect is similar to that of sodium thiopental, but the effect is about 1.8 times stronger. Rapid action and short maintenance time. The induction effect is good, the effect is stable, there is no excitatory phenomenon, and the depth of anesthesia can be controlled by intravenous infusion or multiple uses, there is no significant accumulation, and the patient can recover quickly after waking up. It is used to induce anesthesia and maintain anesthesia.


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