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Phenylacetyl chloride(CAS#103-80-0)

Chemical Property:

Molecular Formula C8H7ClO
Molar Mass 154.59
Density 1.169 g/mL at 25 °C (lit.)
Melting Point 264-266 °C(Solv: N,N-dimethylformamide (68-12-2))
Boling Point 94-95 °C/12 mmHg (lit.)
Flash Point 217°F
Solubility Miscible with alcohol and ether.
Vapor Presure 0.124mmHg at 25°C
Appearance clear liquid
Color Colorless to Light yellow
BRN 742254
Storage Condition 2-8°C
Stability Stable. Reacts with water. Incompatible with amines, most common metals, moisture, strong oxidizing agents.
Sensitive Moisture Sensitive
Refractive Index n20/D 1.5325(lit.)
Physical and Chemical Properties Density 1.16
boiling point 94-95 ° C (12 torr)
refractive index 533-1.102
flash point ° C
Use Used as pharmaceutical, pesticide, Fragrance Intermediates

Product Detail

Product Tags

Hazard Symbols C – Corrosive
Risk Codes R34 – Causes burns
R37 – Irritating to the respiratory system
R14 – Reacts violently with water
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S25 – Avoid contact with eyes.
S27 – Take off immediately all contaminated clothing.
UN IDs UN 2577 8/PG 2
WGK Germany 3
FLUKA BRAND F CODES 21
TSCA Yes
HS Code 29163900
Hazard Class 8
Packing Group II

 

Introduction

Phenylacetyl chloride. The following is an introduction to the properties, uses, preparation methods and safety information of phenylacetyl chloride:

 

Quality:

- Appearance: Phenylacetyl chloride is a colorless to yellowish liquid.

- Solubility: It can be dissolved in many organic solvents, such as methylene chloride, ether and alcohols.

- Stability: Phenylacetyl chloride is sensitive to moisture and will decompose in water.

- Reactivity: Phenylacetyl chloride is an acyl chloride compound that reacts with amines to form amides, which can be used as a raw material for the synthesis of esters.

 

Use:

- Organic synthesis: Phenylacetyl chloride can be used to synthesize corresponding amides, esters and acylated derivatives.

 

Method:

- Phenylacetyl chloride can be prepared by the reaction of phenylacetic acid with phosphorus pentachloride.

 

Safety Information:

- Phenylacetyl chloride is a corrosive chemical that should be avoided in contact with skin, eyes, and mucous membranes. Please wear protective gloves, glasses and goggles when using.

- When operating, avoid inhaling its vapors and ensure its use in a well-ventilated environment.

- When storing, please seal the container tightly and keep away from fire and heat sources. Avoid contact with oxidants, strong alkalis, strong oxidants and acids.

- In case of accidental inhalation or contact, go to a cleaning area immediately and seek medical assistance if necessary.

 


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