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Phenyl {4-[4-(4-Hydroxyphenyl)Piperazin-1-Yl]Phenyl}Carbamate(CAS#184177-81-9)

Chemical Property:

Molecular Formula C23H23N3O3
Molar Mass 389.45
Density 1.296
Boling Point 603.9±55.0 °C(Predicted)
Flash Point 319°C
Vapor Presure 3.52E-15mmHg at 25°C
pKa 12.18±0.30(Predicted)
Storage Condition Sealed in dry,Room Temperature
Refractive Index 1.67
Use Use: Synthesis of posaconazole

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Introduction

4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]carbamate, also known as HPPA, is an organic compound. The following is an introduction to the nature, use, preparation and safety information of HPPA:Quality:Appearance: HPPA is in the form of white crystalline powder.Solubility: HPPA is soluble in commonly used organic solvents such as ethanol and chloroform.Use:Laboratory research: HPPA can be used to synthesize other organic compounds, or as a reagent in organic synthesis and organic chemistry experiments.Method:The preparation method of HPPA is complex and requires high organic synthesis technology. A common preparation method is to convert the benzene 4-aminobenzoate to phenyl 4-aminobenzoate through a hydrogenation reaction of the benzene ether. Then, phenyl 4-aminobenzoate was reacted with 4-hydroxyphenyl-1-piperazine to obtain the final product, 4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]carbamate.Safety Information:There is limited safety information for HPPA, and the necessary safety measures need to be taken when using or handling HPPA:Avoid inhaling HPPA dust and vapours and wear appropriate protective measures such as masks and gloves when using HPPA.Avoid contact with the skin, rinse immediately with water and seek medical attention if it comes into contact with the skin.Avoid accidental ingestion, such as accidental swallowing of HPPA, seek medical attention immediately and carry the substance label for diagnosis.When using and storing HPPA, it should be kept away from fire sources and high-temperature items to avoid fire and explosion.


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