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phenothiazine-2-carbonitrile(CAS#38642-74-9)

Chemical Property:

Molecular Formula C13H8N2S
Molar Mass 224.28
Density 1.38±0.1 g/cm3(Predicted)
Melting Point 191-193°C
Boling Point 427.6±34.0 °C(Predicted)
Flash Point 212.4°C
Solubility Chloroform
Vapor Presure 1.62E-07mmHg at 25°C
Appearance Solid
Color Yellow
pKa -3.04±0.20(Predicted)
Storage Condition Keep in dark place,Sealed in dry,2-8°C
Refractive Index 1.742

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Introduction

phenothiazine-2-carbonitrile is an organic compound containing a phenothiazine nucleus and a cyano group in its structure. The following is a description of its nature, use, formulation and safety information:

 

1. nature:

-Appearance: The phenothiazine-2-carbonitrile is a powdery or crystalline solid.

-Solubility: It can be dissolved in anhydrous ethanol, chloroform and dimethyl sulfoxide, and slightly soluble in water.

-Melting point: about 177-181 ℃.

 

2. use:

-Pharmacology: phenothiazine-2-carbonitrile is an important organic synthesis intermediate, which can be used to synthesize a variety of drugs and physiologically active substances, such as anti-cancer drugs, antibacterial drugs and antidepressants.

-Dye: It can be used as a starting material for the synthesis of organic dyes.

-Photoelectric materials: phenothiazine-2-carbonitrile have application potential in organic photoelectric materials.

 

3. Preparation method:

- phenothiazine-2-carbonitrile can be prepared by the reaction of 2-phenothiazine methanol with hydrocyanic acid. The reaction conditions generally require appropriate acid catalysts.

 

4. Safety Information:

- phenothiazine-2-carbonitrile in the suspended air may produce explosive combustible gas.

-It is irritating to the eyes and skin and should be avoided.

-Use appropriate safety equipment during operation, including protective glasses, protective gloves and respiratory protection.

-In storage and handling, to avoid fire and high temperature environment, to ensure good ventilation. Proper disposal and waste management practices should be followed.

 


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