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p-Toluenesulfonyl isocyanate(CAS#4083-64-1)

Chemical Property:

Molecular Formula C8H7NO3S
Molar Mass 197.21
Density 1.291g/mLat 25°C(lit.)
Melting Point 5°C
Boling Point 144°C10mm Hg(lit.)
Flash Point >230°F
Water Solubility reacts
Vapor Presure 1 mm Hg ( 100 °C)
Appearance Liquid
Specific Gravity 1.291.291
Color Clear colorless to yellow
BRN 391287
Storage Condition under inert gas (nitrogen or Argon) at 2-8°C
Sensitive Moisture Sensitive
Refractive Index n20/D 1.534(lit.)
Physical and Chemical Properties

appearance: colorless transparent liquid Chroma: ≤50APHA

Use Used as an intermediate in the synthesis of pharmaceuticals or pesticides

Product Detail

Product Tags

Hazard Symbols Xn – Harmful
Risk Codes R14 – Reacts violently with water
R36/37/38 – Irritating to eyes, respiratory system and skin.
R42 – May cause sensitization by inhalation
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S28 – After contact with skin, wash immediately with plenty of soap-suds.
S30 – Never add water to this product.
S28A -
UN IDs UN 2206 6.1/PG 3
WGK Germany 1
RTECS DB9032000
FLUKA BRAND F CODES 10
TSCA Yes
HS Code 29309090
Hazard Class 6.1
Packing Group III

 

Introduction

Tosylisocyanate, also known as Tosylisocyanate. The following is an introduction to the properties, uses, preparation methods and safety information of p-toluenesulfonylisocyanate:

 

Quality:

- Appearance: Colorless or light yellow liquid.

- Solubility: Soluble in common organic solvents, such as ethanol, dimethylformamide, etc.

- Stability: Stable, but contact with water and strong alkalis should be avoided.

 

Use:

Tosyl isocyanate is mainly used as a reagent or starting substance in organic synthesis reactions. Tosyl isocyanate can also be used as a catalyst and protective group in synthetic chemistry.

 

Method:

The preparation method of toluenesulfonyl isocyanate is usually obtained by reacting benzoate sulfonyl chloride with isocyanate. The specific steps include the reaction of sulfonyl chloride benzoate with isocyanate in the presence of a base, at room or low temperature. The reaction products are usually extracted and purified by methods such as solvent extraction and crystallization.

 

Safety Information:

- Contact with skin and eyes should be avoided during operation to avoid irritation or injury.

- The operating environment should be well ventilated and avoid inhaling its vapors.

- During storage and carrying, contact with moisture and strong alkalis should be avoided to prevent unsafe reactions.

- Follow relevant safety procedures and measures and wear appropriate personal protective equipment when using and handling tosyl isocyanate.

 


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