p-Toluenesulfonyl isocyanate(CAS#4083-64-1)
Hazard Symbols | Xn – Harmful |
Risk Codes | R14 – Reacts violently with water R36/37/38 – Irritating to eyes, respiratory system and skin. R42 – May cause sensitization by inhalation |
Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S28 – After contact with skin, wash immediately with plenty of soap-suds. S30 – Never add water to this product. S28A - |
UN IDs | UN 2206 6.1/PG 3 |
WGK Germany | 1 |
RTECS | DB9032000 |
FLUKA BRAND F CODES | 10 |
TSCA | Yes |
HS Code | 29309090 |
Hazard Class | 6.1 |
Packing Group | III |
Introduction
Tosylisocyanate, also known as Tosylisocyanate. The following is an introduction to the properties, uses, preparation methods and safety information of p-toluenesulfonylisocyanate:
Quality:
- Appearance: Colorless or light yellow liquid.
- Solubility: Soluble in common organic solvents, such as ethanol, dimethylformamide, etc.
- Stability: Stable, but contact with water and strong alkalis should be avoided.
Use:
Tosyl isocyanate is mainly used as a reagent or starting substance in organic synthesis reactions. Tosyl isocyanate can also be used as a catalyst and protective group in synthetic chemistry.
Method:
The preparation method of toluenesulfonyl isocyanate is usually obtained by reacting benzoate sulfonyl chloride with isocyanate. The specific steps include the reaction of sulfonyl chloride benzoate with isocyanate in the presence of a base, at room or low temperature. The reaction products are usually extracted and purified by methods such as solvent extraction and crystallization.
Safety Information:
- Contact with skin and eyes should be avoided during operation to avoid irritation or injury.
- The operating environment should be well ventilated and avoid inhaling its vapors.
- During storage and carrying, contact with moisture and strong alkalis should be avoided to prevent unsafe reactions.
- Follow relevant safety procedures and measures and wear appropriate personal protective equipment when using and handling tosyl isocyanate.