(S)-1-Boc-3-hydroxypiperidine(CAS#143900-44-1) is a chiral piperidine derivative widely used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of central nervous system (CNS) drugs and antiviral medications.
1. Product Overview
Its unique structure, featuring a Boc-protected amine and a hydroxyl group, makes it a versatile building block for complex molecular synthesis. The compound is highly valued in the pharmaceutical industry for its role in producing enantiomerically pure drugs.
2. Global Market Landscape
The global market for (S)-1-Boc-3-hydroxypiperidine(CAS#143900-44-1) is driven by its applications in drug discovery and development, particularly in the CNS and antiviral therapeutic areas. The demand for this compound is closely tied to the growth of the pharmaceutical sector, especially in regions with strong R&D capabilities.
3. Key Players and Competitive Landscape
Pharmaceutical Companies:
Several leading pharmaceutical companies Utilize(S)-1-Boc-3-hydroxypiperidine(CAS#143900-44-1) in their drug development pipelines. For instance, a major U.S.-based pharmaceutical company has incorporated this compound in the synthesis of a potential CNS drug targeting neurodegenerative diseases. Similarly, a European pharmaceutical giant is exploring its use in antiviral drug candidates. Another global leader in oncology and immunology has also shown interest in this compound for its potential in developing targeted therapies.
Chemical Suppliers:
The supply chain for (S)-1-Boc-3-hydroxypiperidine(CAS#143900-44-1) is dominated by specialized chemical suppliers. A well-known U.S.-based supplier provides high-purity grades of this compound for research and industrial use, catering to the needs of academic institutions and pharmaceutical companies. A Japanese chemical company offers custom synthesis services, ensuring high enantiomeric purity for advanced drug development. Additionally, a German supplier has established a strong presence in the market by providing scalable quantities for large-scale pharmaceutical production.
Emerging Players:
In recent years, several Chinese chemical manufacturers have entered the market, offering cost-effective alternatives. These companies focus on large-scale production, making the compound more accessible to mid-tier pharmaceutical firms and generic drug manufacturers.
4. Applications and Demand Drivers
Pharmaceuticals:
The primary application of (S)-1-Boc-3-hydroxypiperidine(CAS#143900-44-1) is in the synthesis of CNS drugs, such as those targeting Alzheimer’s disease and Parkinson’s disease. Its role in antiviral drug development, particularly for RNA viruses, has also gained attention in recent years.
Fine Chemicals:
The compound is used in the production of chiral catalysts and ligands, which are essential for asymmetric synthesis in fine chemical manufacturing.
Research and Development:
Academic and industrial research laboratories rely on (S)-1-Boc-3-hydroxypiperidine(CAS#143900-44-1) for developing novel therapeutic agents and studying chiral chemistry.
5. Regional Market Insights
North America:
The region is a major consumer of (S)-1-Boc-3-hydroxypiperidine(CAS#143900-44-1), driven by the presence of leading pharmaceutical companies and a strong focus on CNS and antiviral drug development.
Europe:
Europe is another key market, with significant demand from both the pharmaceutical and fine chemical industries. The region’s emphasis on sustainable and green chemistry has also influenced the production methods for this compound.
Asia-Pacific:
The Asia-Pacific region is experiencing rapid growth in demand, fueled by the expansion of the pharmaceutical sector in countries like China and India. Local manufacturers are playing an increasingly important role in meeting this demand.
6. Future Outlook
The market for (S)-1-Boc-3-hydroxypiperidine(CAS#143900-44-1) is expected to grow steadily, driven by increasing demand from the pharmaceutical and fine chemical industries. Key factors influencing future growth include:
Continued investment in CNS and antiviral drug development by pharmaceutical companies.
Expansion of the fine chemical market in emerging economies.
Adoption of sustainable and efficient production methods by chemical suppliers.
XinChem is a global leading supplier of organic chemicals, focusing on providing innovative solutions for the pharmaceutical, chemical, and energy industries. Our expertise in organic synthesis and compound modification enables us to offer high-quality (S)-1-Boc-3-hydroxy piperidine (CAS#143900-44-1) that meets the strictest international standards and has unique properties.
1、Technical Advantages
Advanced Synthesis Process:
XinChem uses cutting-edge chemical synthesis technologies to produce (S)-1-Boc-3-hydroxy piperidine. Take the biocatalysis process as an example. Through the ingenious application of recombinant keto reductase (Kred), N-Boc-piperidin-3-one can be efficiently reduced to obtain (S)-N-Boc-3-hydroxy piperidine (i.e., (S)-1-Boc-3-hydroxy piperidine) with extremely high optical purity. Under the optimized process, the substrate concentration can reach up to 100 g/L, and the enantiomeric excess (ee value) of the product is greater than 99%, while the enzyme loading (w/w) can be controlled below 5%. This advanced process not only greatly improves production efficiency but also ensures the high quality and purity of the product.
Strict Quality Control System:
Starting from the procurement of raw materials, strict screening is carried out to ensure that they meet high standards. At every step of the production process, precise detection points are set up, and advanced analytical instruments such as high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) are used to conduct real-time monitoring and accurate analysis of the product’s purity, impurity content, etc. Only products that fully meet the quality standards will be released to the market, providing reliable product quality assurance for customers.
2、Product Advantages
High Purity:
The (S)-1-Boc-3-hydroxy piperidine product of XinChem has extremely high purity, usually reaching 99%. High purity means that during use, the interference and side reactions caused by impurities are greatly reduced. For application scenarios such as drug synthesis using it as a raw material, it can significantly improve the selectivity and yield of the reaction and reduce the difficulty of subsequent separation and purification, thus improving the overall production efficiency and economic benefits.
Stable Chemical Properties:
Under normal storage and use conditions, this product exhibits good chemical stability. It is not easily decomposed or deteriorated due to environmental factors such as temperature and humidity. This enables customers not to require special harsh conditions during storage and transportation, reducing storage and transportation costs, and also ensuring the consistency of product performance under different environments.
Excellent Optical Purity:
For the chiral compound (S)-1-Boc-3-hydroxy piperidine, optical purity is of vital importance. Through sophisticated technical means, XinChem can ensure that the optical purity of the product reaches an extremely high level. When used in the synthesis of drug molecules with specific chiral requirements, it can precisely control the stereochemical structure of the drug, improve the activity and safety of the drug, and reduce the potential risks brought by unnecessary isomers.
3、Application Fields
(S)-1-Boc-3-hydroxy piperidine (CAS#143900-44-1) is widely used in:
Pharmaceutical Field:
(S)-1-Boc-3-hydroxy piperidine is a key raw material for synthesizing numerous pharmaceutical intermediates. Take ibrutinib as an example. It is a newly approved anti-cancer drug for the treatment of B-cell malignancies such as lymphoma, and (S)-1-Boc-3-hydroxy piperidine plays an indispensable role in its synthesis process. By participating in complex chemical reactions, it constructs specific structural parts of the ibrutinib molecule, thus providing important support for the research and development and production of anti-cancer drugs. In addition, it may also be used in the synthesis of other drug molecules with potential therapeutic value, having broad application prospects in the field of pharmaceutical research and development.
Organic Synthesis Field:
In organic synthesis reactions, (S)-1-Boc-3-hydroxy piperidine is often used as an important structural unit. Due to its unique chemical structure, it can participate in various types of chemical reactions, such as nucleophilic substitution reactions and condensation reactions, for constructing organic compounds with specific functions and structures. Whether it is for synthesizing materials with special properties or for exploring new organic reaction paths and mechanisms, (S)-1-Boc-3-hydroxy piperidine can play an important role, providing a powerful tool for organic synthesis chemists.
4、Service Support
Professional Technical Consultation:
XinChem has a team composed of senior chemists and technical experts who have in-depth understanding and rich experience in the properties, applications, and related technical issues of (S)-1-Boc-3-hydroxy piperidine. Whenever customers encounter any technical problems during the use of the product, they can consult this team at any time. The team will provide detailed, accurate, and professional answers and suggestions to help customers use the product better and optimize related experimental and production processes.
Flexible Order Service:
Whether customers need small-scale samples for trial production or large-scale industrial production orders, XinChem can meet their needs. The company has strong production capacity and an efficient supply chain management system, which can quickly adjust the production plan according to customers’ needs to ensure timely order delivery. At the same time, during the order processing, it maintains close communication with customers, promptly feedbacks the order progress, and enables customers to know the order status at any time, providing a reassuring purchasing experience.
After-sales Guarantee:
If customers find any quality problems after receiving the product, XinChem promises to provide timely and effective solutions. The company will quickly arrange professional personnel to investigate and analyze the problem. If it is indeed a product quality problem, it will provide customers with services such as product replacement and refund to protect customers’ rights and interests and maintain the company’s good reputation and image.
5、Reasons for Choosing XinChem
Double Excellence in Technology and Product:
With advanced technical advantages, XinChem produces (S)-1-Boc-3-hydroxy piperidine products with high purity, stable chemical properties, and excellent optical purity, which can meet customers’ stringent requirements for product quality in different application scenarios and provide a solid material foundation for customers’ research and development and production work.
All-round Service Guarantee:
From professional technical consultation to flexible order service and then to a complete after-sales guarantee, XinChem provides customers with a one-stop high-quality service experience. It enables customers to have no worries during the procurement and use of the product and focus on the development of their own business.
Industry Experience and Reputation:
XinChem has accumulated rich industry experience in the chemical field. During the long-term development process, it has established good cooperative relationships with many customers and won a good reputation. Choosing XinChem means that customers can obtain more reliable products and services with the help of the company’s rich experience and mature system, reduce cooperation risks, and achieve mutual benefit and win-win results.
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Post time: Mar-06-2025