Nalpha-Fmoc-Ndelta-trityl-L-glutamine (CAS# 132327-80-1)
Risk and Safety
| Hazard Symbols | Xi – Irritant |
| Risk Codes | R36/37/38 – Irritating to eyes, respiratory system and skin. R53 – May cause long-term adverse effects in the aquatic environment R43 – May cause sensitization by skin contact |
| Safety Description | S22 – Do not breathe dust. S24/25 – Avoid contact with skin and eyes. S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S61 – Avoid release to the environment. Refer to special instructions / safety data sheets. S37 – Wear suitable gloves. S24 – Avoid contact with skin. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-21 |
| HS Code | 2924 29 70 |
132327-80-1 - Introduction
This compound is a white crystalline solid, odorless. It has a melting point of about 178-180°C and is soluble in organic solvents such as dimethylsulfoxide (DMSO) and dimethylformamide (DMF), but insoluble in water.
Use:
FMOC-γ-trityl-L-Glu-OH is commonly used in the field of peptide synthesis in chemical synthesis. It can be used as a protecting group to protect the glutamic acid residue in the peptide chain, thereby controlling the assembly and modification of the peptide chain.
Preparation Method:
The preparation of FMOC-γ-trityl-L-Glu-OH is usually obtained by chemical synthesis. Briefly, it can be obtained by condensation reaction of tritylglycine with fluorenecarboxylic acid.
Safety Information:
FMOC-γ-trityl-L-Glu-OH has no obvious toxicity under normal conditions. However, as with other chemical reagents, use and handle them in accordance with proper laboratory safety procedures, avoid direct contact with skin and eyes, and ensure that they are handled in a well-ventilated environment.
