N-tert-Butoxacarbonyl-O-benzyl-L-threonine (CAS# 15260-10-3)

Introduction
N-Boc-O-benzyl-L-threonine is an organic compound. The following is an introduction to its nature, use, manufacturing method and safety information:

Quality:
N-Boc-O-benzyl-L-threonine is a white or off-white crystalline solid, soluble in common organic solvents such as ethanol, dimethylformamide, chloroform, etc.

Use:
N-Boc-O-benzyl-L-threonine is an important intermediate in organic synthesis and is commonly used in the synthesis of peptides and proteins. It can be used as a protective group in solid-phase synthesis, liquid-phase synthesis and ethanolamine-mediated synthesis to prevent the side reaction of threonine in the reaction process, so as to improve the selectivity and yield of the reaction.

Method:
The preparation of N-Boc-O-benzyl-L-threonine is generally made by chemical synthesis. Threonine is acylated with N-tert-butoxycarbonyl (Boc-O-benzyl) and activators such as N,N-diisopropylethylamine (DIPEA) or carbodiimide (DCC) are added. After the reaction, N-Boc-O-benzyl-L-threonine was obtained.

Safety Information:
N-Boc-O-benzyl-L-threonine has a high safety profile, but as an organic compound, the following safety precautions should still be noted: avoid contact with skin, eyes and respiratory system; Wear protective gloves, goggles, and masks when operating; Operate in a well-ventilated laboratory; Avoid contact with oxidants and acids when storing. If it is accidentally touched or inhaled, it should be washed or treated with medical attention in time.