N N’-Di-Boc-L-lysine hydroxysuccinimide ester（CAS# 30189-36-7)

Introduction

N,N’-Di-Boc-L-lysine hydroxysuccinimide ester is a compound with a chemical formula of C18H30N4O7 and a molecular weight of 414.45. The following are some of the properties, uses, preparation and safety information of the compound:

Nature:

-Appearance: White solid

-Solubility: Soluble in organic solvents such as dimethyl sulfoxide (DMSO) and Dimethyl Formamide (DMF)

-Melting Point: about 80-90 ℃

Use:

- N,N’-Di-Boc-L-lysine hydroxysuccinimide ester is commonly used as a protecting group in peptide synthesis and can be used to synthesize polypeptides and proteins

-It can introduce succinimide (Boc) protecting group on the carboxyl group of amino acid, and then introduce other groups through nucleophilic substitution reaction to synthesize the desired polypeptide

Method:

- N,N’-Di-Boc-L-lysine hydroxysuccinimide ester can be obtained by reacting the compound N,N’-di-tert-butoxycarbonyl-L-lysine (N,N’-Di-Boc-L-lysine) with hydroxysuccinimide ester

-The reaction is usually carried out at room temperature, the reaction time is several hours to several days, and the product is purified by crystallization to obtain the desired product

Safety Information:

- N,N’-Di-Boc-L-lysine the safety information of hydroxysuccinimide ester is limited, it is generally considered to have low toxicity in a laboratory environment

-During handling and operation, appropriate protective measures should be taken, such as wearing protective glasses and gloves to ensure good ventilation

-It is necessary to avoid contact of the compound with skin, eyes and mucous membranes. If there is contact, rinse immediately with plenty of water

-During storage and handling, avoid contact with oxidants to avoid fire or explosion