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N-Fmoc-N-4-methoxy-2,3,6-trimethylbenzenesulfonyl-L-arginine CAS 98930-01-9

Chemical Property:

Molecular Formula C31H36N4O7S
Molar Mass 608.71
Density 1.35±0.1 g/cm3(Predicted)
Appearance Powder
Color White
pKa 3.83±0.21(Predicted)
Storage Condition Sealed in dry,Store in freezer, under -20°C
Sensitive Moisture Sensitive
Refractive Index 1.634

Product Detail

Product Tags

Risk and Safety

Risk Codes R45 – May cause cancer
R46 – May cause heritable genetic damage
R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S53 – Avoid exposure – obtain special instructions before use.
S22 – Do not breathe dust.
S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany 3
FLUKA BRAND F CODES 10-21
HS Code 29350090
Hazard Class IRRITANT

Reference Information

Use N-Fmoc-N ‘-(4-methoxy-2, 3, 6-trimethylbenzenesulfonyl) L-arginine is an amino acid derivative and is useful as a Biochemical reagent.

 

Introduction
N-Fmoc-N’-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine is an arginine derivative. Here is some information about its properties, uses, manufacturing methods, and safety:

Quality:
3. Appearance: white crystalline solid
5. Solubility: soluble in organic solvents such as dimethyl sulfoxide (DMSO), dimethylformamide (DMF), etc.

Use:
N-Fmoc-N’-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine is mainly used as a protective group in solid phase peptide synthesis (SPPS) to prevent arginine from misreacting with other reactants,  and can also be used to synthesize peptides and proteins.

Method:
The preparation of N-Fmoc-N’-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine is generally carried out by chemical synthesis. The main steps include the synthesis of N-Fmoc-arginine, benzoxazolesulfonyl chloride reagent and methanol reaction to obtain N-Fmoc-N’-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine.

Safety Information:
1. N-Fmoc-N’-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine is a chemical and should be followed in accordance with laboratory safety procedures;
2. Wear protective glasses and gloves when using to avoid direct contact and inhalation;
3. In case of accidental contact with skin or eyes, rinse immediately with plenty of water and seek medical treatment;
4. When storing, it should be sealed and kept away from fire and oxidant.


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