N-Cbz-D-glutamic acid alpha-benzyl ester（CAS# 65706-99-2)
| Safety Description | 24/25 – Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29242990 |
Introduction
Z-D-glutamic acid 1-benzyl ester is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: The compound is white crystal or crystalline powder.
-Solubility: Soluble in some organic solvents, such as ethanol, dimethyl sulfoxide and chloroform.
-Melting point: The melting point of the compound is about 145-147 degrees Celsius.
-Molecular formula: C16H19NO5
-Molecular Weight: 309.33
-Structure: It contains benzyl and amino acid groups.
Use:
-Chemical reagent: In organic synthesis, it can be used as a chemical reagent, especially suitable for the synthesis of amino acids.
-Drug research: In drug research, it is used as a precursor of anti-tumor drugs, or used to study kinase inhibitors.
Preparation Method:
Z-D-glutamic acid 1-benzyl ester can be prepared by the following steps:
1. Benzyl alcohol and dimethyl carbamate react under alkaline conditions to produce benzylethanolamine.
2. esterification of benzylethanolamine with D-glutamic acid can obtain Z-D-glutamic acid 1-benzyl ester.
Safety Information:
-The compound needs to be handled and used with appropriate laboratory safety measures.
-Avoid contact with skin, eyes and respiratory tract.
-Use personal protective equipment such as lab coats, gloves and protective glasses.
-It should be operated in a well-ventilated place to avoid inhaling its dust or vapor.
-Follow the correct waste disposal procedures to avoid pollution to the environment.
