N-BOC-O-Benzyl-L-serine(CAS# 23680-31-1)
Hazard Symbols | Xn – Harmful |
Risk Codes | R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 – Irritating to eyes, respiratory system and skin. |
Safety Description | S24/25 – Avoid contact with skin and eyes. S36 – Wear suitable protective clothing. S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
WGK Germany | 3 |
TSCA | Yes |
HS Code | 2924 29 70 |
Hazard Class | IRRITANT |
Introduction
Trit-butoxycarbonyl-L-seric acid benzyl ester (also known as BOC-L-serine benzyl ester) is an organic compound. It has the following properties:
1. Appearance: white to light yellow crystals or crystalline powder.
Trit-butoxycarbonyl-L-seric acid benzyl is mainly used for peptide synthesis and peptide synthesis reactions in the field of organic synthesis. It acts as a protecting group in peptide chain elongation reactions to protect the side chain functional groups of amino acids. During the synthesis process, when other amino acids in the target peptide sequence do not need to be changed in the reaction, tert-butoxycarbonyl-L-seric acid benzyl can effectively protect L-serine.
The method of preparing tert-butoxycarbonyl-L-serene benzyl is generally through the activation and esterification reaction of amino acids. The specific preparation method can be to react L-serine with tert-butoxycarbonyl chlorinator to form tert-butoxycarbonyl amino acid salt, and then react with benzyl alcohol to obtain tert-butoxycarbonyl-L-serene benzyl.
Safety Information: Trit-butoxycarbonyl-L-seric acid benzyl is generally relatively safe under correct operation. It can be irritating to the eyes and skin and requires proper precautions when operating. It needs to be operated in a well-ventilated area and avoid inhalation or contact. During storage, it should be kept tightly sealed and away from heat and fire.