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N-BOC-O-Benzyl-L-serine(CAS# 23680-31-1)

Chemical Property:

Molecular Formula C15H21NO5
Molar Mass 295.33
Density 1.1454 (rough estimate)
Melting Point 58-60°C(lit.)
Boling Point 437.02°C (rough estimate)
Specific Rotation(α) 21.5 º (c=2, ethanol)
Flash Point 229.7°C
Vapor Presure 4.07E-09mmHg at 25°C
Appearance White crystal or powder
Color White to Almost white
BRN 3064461
pKa 3.53±0.10(Predicted)
Storage Condition Keep in dark place,Sealed in dry,Room Temperature
Refractive Index 22 ° (C=2, EtOH)
MDL MFCD00066063
Physical and Chemical Properties White crystalline powder; Insoluble in water and petroleum ether, soluble in ethyl acetate, acetic acid and ethanol; mp is 56-58 ℃; Specific optical rotation [α]20D 20 °(0.5-2.0 mg/ml, acetic acid).

Product Detail

Product Tags

Hazard Symbols Xn – Harmful
Risk Codes R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S24/25 – Avoid contact with skin and eyes.
S36 – Wear suitable protective clothing.
S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 3
TSCA Yes
HS Code 2924 29 70
Hazard Class IRRITANT

 

Introduction

Trit-butoxycarbonyl-L-seric acid benzyl ester (also known as BOC-L-serine benzyl ester) is an organic compound. It has the following properties:

 

1. Appearance: white to light yellow crystals or crystalline powder.

 

Trit-butoxycarbonyl-L-seric acid benzyl is mainly used for peptide synthesis and peptide synthesis reactions in the field of organic synthesis. It acts as a protecting group in peptide chain elongation reactions to protect the side chain functional groups of amino acids. During the synthesis process, when other amino acids in the target peptide sequence do not need to be changed in the reaction, tert-butoxycarbonyl-L-seric acid benzyl can effectively protect L-serine.

 

The method of preparing tert-butoxycarbonyl-L-serene benzyl is generally through the activation and esterification reaction of amino acids. The specific preparation method can be to react L-serine with tert-butoxycarbonyl chlorinator to form tert-butoxycarbonyl amino acid salt, and then react with benzyl alcohol to obtain tert-butoxycarbonyl-L-serene benzyl.

 

Safety Information: Trit-butoxycarbonyl-L-seric acid benzyl is generally relatively safe under correct operation. It can be irritating to the eyes and skin and requires proper precautions when operating. It needs to be operated in a well-ventilated area and avoid inhalation or contact. During storage, it should be kept tightly sealed and away from heat and fire.


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