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N-Boc-D-proline(CAS# 37784-17-1)

Chemical Property:

Molecular Formula C10H17NO4
Molar Mass 215.25
Density 1.1835 (rough estimate)
Melting Point 134-137 °C (lit.)
Boling Point 355.52°C (rough estimate)
Specific Rotation(α) 60 º (c=2, acetic acid)
Flash Point 157.7°C
Vapor Presure 2E-05mmHg at 25°C
Appearance White crystalline powder
Color White to off-white
BRN 479316
pKa 4.01±0.20(Predicted)
Storage Condition 2-8°C
Sensitive Sensitive to heat
Refractive Index 60 ° (C=2, AcOH)
MDL MFCD00063226

Product Detail

Product Tags

Safety Description 24/25 – Avoid contact with skin and eyes.
WGK Germany 3
HS Code 2933 99 80

 

Introduction

N-Boc-D-proline is an organic compound with the following properties:

 

Appearance: colorless crystalline or white powder form.

Solubility: Soluble in some organic solvents.

 

The main use of N-Boc-D-proline is as a starting compound or intermediate in organic synthesis.

 

Methods for the preparation of N-Boc-D-proline include:

 

D-proline is reacted with iodophenyl carboxylic acid to form D-proline benzyl ester.

D-proline benzyl ester is reacted with tert-butyldimethylsilylboron fluoride (Boc2O) to generate N-Boc-D-proline.

 

Avoid inhaling dust or contact with skin, eyes, and clothing.

Appropriate personal protective equipment such as lab gloves, protective eyewear, and protective masks should be worn when in use.

When storing, it should be kept away from fire sources and oxidants, and avoid high temperatures and direct sunlight.

When using or handling compounds, comply with safe laboratory practices and handle and store them in accordance with relevant laws and regulations.

 


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