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N-Carbobenzyloxy-L-proline(CAS# 1148-11-4)

Chemical Property:

Molecular Formula C13H15NO4
Molar Mass 249.26
Density 1.1952 (rough estimate)
Melting Point 75-77°C
Boling Point 392.36°C (rough estimate)
Specific Rotation(α) -60 º (c=2,AcOH)
Flash Point 215.3°C
Solubility Solubility in methanol, almost transparency.
Vapor Presure 3.06E-08mmHg at 25°C
Appearance White to bright yellow crystals
Color White to off-white
BRN 88579
pKa 3.99±0.20(Predicted)
Storage Condition Sealed in dry,Room Temperature

Product Detail

Product Tags

Cbz-L-Proline, whose full name is L-Proline-9-Butyroyl Ester, is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of Cbz-L-proline:

Quality:
- Appearance: White crystalline or crystalline powder.
- Salt solubility: soluble in acids, insoluble in water.

Use:
- Cbz-L-proline is often used as a protective group in organic synthesis to protect amino groups (NH₂) in amino acids.
- It is mainly used in the chemical synthesis of peptides and proteins.

Method:
The preparation of Cbz-L-proline is generally done by the following steps:
1. Proline is reacted with chloroformate-9-butyl ester under alkaline conditions to obtain a substrate.
2. Substrate is treated under acidic conditions to generate Cbz-L-proline.

Safety Information:
- Cbz-L-Proline is a chemical and should be handled with care. Take care to avoid contact with skin and eyes, and avoid inhalation.
- Wear appropriate personal protective equipment such as lab gloves and goggles when in use.
- Store tightly sealed and avoid direct sunlight and high temperatures.
- After use and handling, follow local regulations for chemical disposal.


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