N-Carbobenzyloxy-L-proline(CAS# 1148-11-4)
Cbz-L-Proline, whose full name is L-Proline-9-Butyroyl Ester, is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of Cbz-L-proline:
Quality:
- Appearance: White crystalline or crystalline powder.
- Salt solubility: soluble in acids, insoluble in water.
Use:
- Cbz-L-proline is often used as a protective group in organic synthesis to protect amino groups (NH₂) in amino acids.
- It is mainly used in the chemical synthesis of peptides and proteins.
Method:
The preparation of Cbz-L-proline is generally done by the following steps:
1. Proline is reacted with chloroformate-9-butyl ester under alkaline conditions to obtain a substrate.
2. Substrate is treated under acidic conditions to generate Cbz-L-proline.
Safety Information:
- Cbz-L-Proline is a chemical and should be handled with care. Take care to avoid contact with skin and eyes, and avoid inhalation.
- Wear appropriate personal protective equipment such as lab gloves and goggles when in use.
- Store tightly sealed and avoid direct sunlight and high temperatures.
- After use and handling, follow local regulations for chemical disposal.