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N-alpha-(tert-Butoxycarbonyl)-L-lysine (CAS# 13734-28-6)

Chemical Property:

Molecular Formula C11H22N2O4
Molar Mass 246.3
Density 1.1313 (rough estimate)
Melting Point ~205°C (dec.)(lit.)
Boling Point 389.3°C (rough estimate)
Specific Rotation(α) 22 º (c=2, CH3OH)
Flash Point 203.5°C
Water Solubility Soluble in water. Slightly soluble in methanol.
Solubility Acetic Acid (Slightly), Methanol (Slightly, Sonicated), Water (Slightly, Heated,
Vapor Presure 5.65E-08mmHg at 25°C
Appearance White solid
Color White
BRN 4252546
pKa 3.92±0.21(Predicted)
Storage Condition Keep in dark place,Sealed in dry,Room Temperature
Sensitive Sensitive to heat
Refractive Index 21.5 ° (C=2, MeOH)
MDL MFCD00038203

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Risk and Safety

Hazard Symbols Xn – Harmful
Risk Codes R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S24/25 – Avoid contact with skin and eyes.
S36 – Wear suitable protective clothing.
S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 3
HS Code 2924 19 00
Hazard Class IRRITANT

N-alpha-(tert-Butoxycarbonyl)-L-lysine (CAS# 13734-28-6) introduction

N-Boc-L-lysine is an amino acid derivative that contains a protective group Boc (t-butoxycarbonyl) in its structure. The following is an introduction to the properties, uses, preparation methods, and safety information of N-Boc-L-lysine:

nature:
-Appearance: White or off white crystalline powder
-Solubility: Dissolves in common organic solvents such as methanol, ethanol, and dichloromethane.

Purpose:
-It can serve as a protective group for L-lysine, protecting its amino or carboxyl groups under certain reaction conditions to prevent unnecessary reactions from occurring.

Manufacturing method:
-The synthesis of N-Boc-L-lysine is mainly obtained through the protective group reaction of L-lysine. The common preparation method is to first react L-lysine with Boc2O (t-butoxycarbonyl dicarboxylic anhydride) or Boc-ONH4 (t-butoxycarbonyl hydroxylamine hydrochloride) to form N-Boc-L-lysine with a protective group of Boc.

Security information:
-N-Boc-L-lysine is a chemical, and safety precautions should be taken when using it, and relevant safety guidelines should be followed.
-It may be irritating to the skin, eyes, and respiratory system, and should be immediately rinsed with plenty of water after contact.
-When handling and storing, avoid contact with oxidants, strong bases, and acids, avoid large-scale storage, and avoid high temperatures and sources of fire.
-Please handle and dispose of unwanted or expired chemicals in the correct manner to reduce the risk of environmental pollution.


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