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N-Acetyl-L-leucine (CAS# 1188-21-2)

Chemical Property:

Molecular Formula C8H15NO3
Molar Mass 173.21
Density 1.1599 (rough estimate)
Melting Point 187-190°C(lit.)
Boling Point 303.86°C (rough estimate)
Specific Rotation(α) -24.5 º (c=4, MeOH)
Flash Point 177.4°C
Water Solubility 0.81 g/100 mL (20 ºC)
Solubility Soluble in water (partly), ethanol (5%), and methanol.
Vapor Presure 1.77E-06mmHg at 25°C
Appearance Solid
Color White
BRN 1724849
pKa 3.67±0.10(Predicted)
Storage Condition Sealed in dry,Room Temperature

Product Detail

Product Tags

N-acetyl-L-leucine is an amino acid derivative. It is a compound obtained by the reaction of L-leucine with an acetylaylating agent. N-acetyl-L-leucine is a white crystalline powder that is soluble in water and alcohol-based solvents. It is stable under neutral and weakly alkaline conditions, but hydrolyzed under strong acidic conditions.

A common way to prepare N-acetyl-L-leucine is by reacting L-leucine with an appropriate acetylating agent, such as acetic anhydride, under alkaline conditions. This reaction is usually performed at room temperature.

Safety Information: N-acetyl-L-leucine is a relatively safe compound, but care should still be taken to follow proper handling methods when using it. Avoid inhaling the powder and contact with the skin, eyes and mucous membranes. Keep it well ventilated during use and storage, and avoid contact with oxidants and strong acids. In case of accidental contact or ingestion, emergency treatment should be taken immediately and a doctor should be consulted for further management.


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