Morniflumate(CAS#65847-85-0)
Morniflumate(CAS#65847-85-0)
pharmachologic effect
Anti-inflammatory effect: It reduces arachidonic acid metabolism by inhibiting cyclooxygenase and 5-lipoxygenase pathways, which in turn reduces the synthesis of inflammatory mediators such as prostaglandins, leukotrienes, etc., and exerts anti-inflammatory effects.
Antipyretic effect: It can act on the body temperature regulation center, dilate the peripheral blood vessels, increase the blood flow to the skin, promote sweating, increase heat dissipation, and thus exert an antipyretic effect.
Analgesic effect: It can inhibit the synthesis of prostaglandins at the site of inflammation, reduce the stimulation of nerve endings by inflammatory reactions, and exert peripheral analgesic effects.
Clinical application
Inflammatory treatment in adults: It is used to treat inflammatory diseases affecting the respiratory tract, otolaryngology system, genitourinary tract and osteoarticular system.
Treatment of Pediatric Related Diseases: In Italy, maniflurate can also be used to treat pain associated with inflammation of the ear, nose and throat and gastrointestinal tract in children, especially upper respiratory tract infections.