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Methyl L-tryptophanate hydrochloride (CAS# 7524-52-9)

Chemical Property:

Molecular Formula C12H15ClN2O2
Molar Mass 254.71
Melting Point 218-220°C(lit.)
Boling Point 390.6°C at 760 mmHg
Specific Rotation(α) 18 º (c=5 CH3OH)
Flash Point 190°C
Solubility DMSO (Slightly), Methanol (Sparingly)
Vapor Presure 2.62E-06mmHg at 25°C
Appearance White-like powder
Color White to off-white
BRN 4240280
Storage Condition Keep in dark place,Sealed in dry,Room Temperature
Sensitive Sensitive to light
Refractive Index 19.5 ° (C=5, MeOH)
MDL MFCD00066134
Use Used for biochemical reagents, pharmaceutical intermediates.

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Risk and Safety

Hazard Symbols Xi – Irritant
Safety Description S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
WGK Germany 3
HS Code 29339900
Hazard Class IRRITANT

 

 Introduction

L-tryptophan methyl ester hydrochloride is a compound with the chemical formula C12H14N2O2 · HCl. The following is an introduction to the nature, use, formulation and safety information of L-tryptophan methyl ester hydrochloride:Nature:
-Appearance: L-tryptophan methyl ester hydrochloride as a white crystalline solid.
-Solubility: It has low solubility in water and high solubility in anhydrous ethanol, chloroform and acetic acid.
-Melting point: Its melting point is about 243-247°C.
-Optical rotation: L-tryptophan methyl ester hydrochloride has optical rotation, and its optical rotation is 31 ° (c = 1, H2O).

Use:
- L-tryptophan methyl ester hydrochloride are important reagents in the field of biochemistry and are often used to synthesize specific protein or polypeptide sequences.
-It can be used to study the role of tryptophan in protein structure, function and metabolism.
- L-tryptophan methyl ester hydrochloride can also be used as a drug intermediate for the synthesis of tryptophan-related drugs.

Preparation Method:
The preparation method of L-tryptophan methyl ester hydrochloride can be obtained by the reaction of L-tryptophan and methyl formate. First, L-tryptophan was esterified with methyl formate to obtain L-tryptophan methyl ester, and then reacted with hydrochloric acid to obtain L-tryptophan methyl ester hydrochloride.

Safety Information:
- L-tryptophan the safety information of the methyl ester hydrochloride is limited, appropriate safety measures need to be taken during use.
-in the operation should pay attention to avoid contact with skin and eyes, such as contact occurs, should immediately rinse with plenty of water.
-Need to operate in a well-ventilated environment to prevent its vapor inhalation.
-The storage of L-tryptophan methyl ester hydrochloride should avoid direct sunlight and humid environment, and it is best to store them in a dry and cool place.


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