Methyl 4 6-dichloronicotinate（CAS# 65973-52-6)
| Hazard Symbols | Xn – Harmful |
| Risk Codes | 22 – Harmful if swallowed |
| Safety Description | 24/25 – Avoid contact with skin and eyes. |
| HS Code | 29339900 |
| Hazard Class | IRRITANT |
Introduction
Methyl 4,6-dichloronotinic acid. The following is an introduction to its nature, use, preparation method and safety information:
Quality:
- Appearance: Methyl 4,6-dichloronotinate is a colorless to light yellow liquid.
- Solubility: It is soluble in organic solvents such as alcohols, ethers, and ketones, and insoluble in water.
- Odor: It has a pungent odor.
Use:
- Pesticide intermediates: Methyl 4,6-dichloronotinic acid is often used as a pesticide intermediate in the synthesis of various insecticides, herbicides and fungicides.
- Chemical synthesis: It can also be used as an important raw material in organic synthesis, such as the synthesis of esters, amides and heterocyclic compounds.
Method:
- Methyl 4,6-dichloronicotinate can be obtained by chlorination of nicotinyl chloride (3-chloropyridine-4-formyl chloride). The specific steps include reacting nicotinyl chloride with methanol to produce methyl 4,6-dichloronicotinate.
Safety Information:
- Risk warning: Methyl 4,6-dichloronicotinate is an organochlorine compound with high potential toxicity. Prolonged exposure, inhalation, or skin contact can be a health hazard.
- Protective measures: Wear appropriate protective gloves, goggles, and protective clothing when in use or contact.
- Storage Caution: It should be stored in a dry, cool, well-ventilated place. Avoid contact with oxidants, acids and other substances.
