Methyl 2-bromomethyl-3-nitrobenzoate （CAS# 98475-07-1)
| UN IDs | UN 3261 8/PG III |
| Hazard Class | 8 |
| Packing Group | III |
Introduction
Methyl 2-bromomethyl-3-nitrobenzoate.
Quality:
1. Appearance: colorless liquid or white crystalline solid;
4. Density: about 1.6-1.7 g/ml;
5. Solubility: soluble in organic solvents, such as alcohols, ethers and ketones.
Use:
Methyl 2-bromomethyl-3-nitrobenzoate is often used as an intermediate of pesticides, can be used in the synthesis of pesticides such as methyl besylsulfonylcarboxyl, and can also be used as a synthetic intermediate of glyphosate.
Method:
Methyl 2-bromomethyl-3-nitrobenzoate can be prepared by chloromethylation and nitrification. The specific steps are as follows: methyl benzoate is reacted with acetic acid and phosphorus trichloride at low temperature to obtain methyl 2-chloromethylbenzoate; Then, methyl 2-chloromethylbenzoate is introduced into the nitro group by nitrification of lead nitrate to give methyl 2-bromomethyl-3-nitrobenzoate.
Safety Information:
1. Methyl 2-bromomethyl-3-nitrobenzoate is flammable at high temperature and open flame, so high temperature and open flame should be avoided.
2. Wear chemical protective glasses and gloves when using to avoid contact with skin and inhalation of gases.
4. When storing, it should be sealed and kept away from heat, fire and oxidants.
