Mesitylene(CAS#108-67-8)
| Risk Codes | R10 - Flammable R37 - Irritating to the respiratory system R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R39/23/24/25 - R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R11 - Highly Flammable R37/38 - Irritating to respiratory system and skin. |
| Safety Description | S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. S16 - Keep away from sources of ignition. S7 - Keep container tightly closed. |
| UN IDs | UN 2325 3/PG 3 |
| WGK Germany | 2 |
| RTECS | OX6825000 |
| FLUKA BRAND F CODES | 10 |
| TSCA | Yes |
| HS Code | 29029080 |
| Hazard Note | Irritant/Flammable |
| Hazard Class | 3 |
| Packing Group | III |
| Toxicity | LD50 (inhalation) for rats 24 g/m3/4-h (quoted, RTECS, 1985). |
Product Name and CAS Number
Mesitylene 1 3 5 Trimethylbenzene | CAS 108 67 8
One Line Sourcing Position
High purity Mesitylene for high boiling point solvent applications and organic synthesis intermediates.
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Specification
Purity by GC: 99.0 percent minimum, typical batch 99.2 to 99.6 percent
Appearance: Colorless clear liquid
Density at 20 deg C: 0.862 to 0.866 g per mL
Refractive index nD20: 1.497 to 1.499
Boiling point: 163 to 166 deg C
Water content Karl Fischer: 0.05 percent maximum
Color APHA: 20 maximum
Residue on evaporation: 0.005 percent maximum
Sulfur content: Less than 2 ppm
Stock Status: In Stock in US warehouse and China hub
Available Quantity and Lead Time
Regular supply: 1 kg to 30 metric tons per shipment
Lead time: 2 to 4 days for standard packaging; bulk orders require 7 to 10 days
Document Support
COA SDS HPLC chromatogram NMR spectrum Mass spectrum MS available upon request
Application
Mesitylene is a high boiling aromatic solvent widely used in industrial coatings, paints, and printing inks where slow evaporation and high solvency are required. It serves as an effective replacement for xylene or toluene in applications needing higher flash point and reduced volatility. In organic synthesis, mesitylene is utilized as a solvent for high temperature reactions such as Suzuki couplings, Friedel Crafts acylations, and transition metal catalyzed polymerizations due to its thermal stability (up to 160 deg C). The compound is also a precursor for the production of trimellitic acid (benzene 1 2 4 tricarboxylic acid) via oxidation, which is used in high performance plasticizers, polyimides, and powder coating resins. In pharmaceutical research, mesitylene acts as a non polar solvent for crystallization and as an internal standard in NMR spectroscopy (due to its sharp singlet at 6.8 ppm). It is employed in the synthesis of synthetic musks (e.g., trinitro mesitylene derivatives), UV stabilizers, and photoinitiators for UV curable systems. Additionally, mesitylene finds use as a component in electrolyte formulations for lithium ion batteries, as a cleaning agent for electronic components, and as a reference material in chromatographic analysis.
Custom Synthesis Support
We offer custom synthesis for mesitylene derivatives including brominated, nitrated, and sulfonated products. Share your technical datasheet for feasibility review.
Packaging and Shipping
Available in 1 L, 5 L, 20 L, 200 L steel drums or IBC totes. Custom packaging such as amber glass bottles under nitrogen is supported. Fastest dispatch within 7 days after order confirmation. Flammable liquid Class 3, UN 2325, PG III. Store away from oxidizers and heat sources. Grounding required during transfer.
Why XinChem
XinChem provides mesitylene with strict control of purity and low moisture content for US customers. Our ISO 9001 certified facility monitors every batch by GC and Karl Fischer analysis, ensuring consistent performance as a high boiling solvent and synthesis intermediate. We maintain a buffer stock of 15 metric tons in US warehouses for emergency deliveries within 48 hours. Each order includes a full documentation package: COA, SDS, GC chromatograms, and NMR spectra accessible through our online portal. Our technical support team assists with solvent selection, handling recommendations, and regulatory compliance including TSCA, EINECS, and clean air act VOC regulations. For contract customers, we offer quarterly price locks and consignment inventory to reduce supply chain risk. Trusted by over 200 coatings, pharmaceutical, and fine chemical companies in North America. We also provide free sample evaluation for qualified R&D projects and a price match guarantee against any valid competitor quote for equivalent quality. Additionally, we offer custom distillation to achieve 99.5 percent plus purity for electronic grade applications.
FAQ
Q1 How should mesitylene be stored?
A Store in a cool, well ventilated area away from ignition sources and strong oxidizers. Keep container tightly sealed. Shelf life is 36 months under recommended conditions.
Q2 What purity grades do you supply?
A Standard grade is 99.0 percent by GC. We also supply 99.5 percent and 99.8 percent grades for synthesis and electronic cleaning applications.
Q3 Is mesitylene soluble in water?
A Insoluble in water. Miscible with organic solvents such as toluene, xylene, hexane, and diethyl ether.
Q4 Do you provide sample quantities for formulation testing?
A Yes, free samples of 500 mL are available for qualified US companies. Shipping fee applies for small quantities.
Q5 What are the common impurities in mesitylene?
A Main impurities are pseudocumene (1 2 4 trimethylbenzene) and hemimellitene (1 2 3 trimethylbenzene), each typically below 0.3 percent.
Q6 Can mesitylene be used as a substitute for toluene in high temperature reactions?
A Yes, its higher boiling point (163 deg C vs 110 deg C for toluene) allows reactions at elevated temperatures without pressure vessels. Confirm compatibility with your reagents.








