Levodopa(CAS# 59-92-7)
Hazard Symbols | Xn – Harmful |
Risk Codes | R22 – Harmful if swallowed R36/37/38 – Irritating to eyes, respiratory system and skin. R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed. |
Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 – Wear suitable protective clothing. S24/25 – Avoid contact with skin and eyes. |
WGK Germany | 3 |
RTECS | AY5600000 |
FLUKA BRAND F CODES | 10-23 |
TSCA | Yes |
HS Code | 29225090 |
Toxicity | LD50 in mice (mg/kg): 3650 ±327 orally, 1140 ±66 i.p., 450 ±42 i.v., >400 s.c.; in male, female rats (mg/kg): >3000, >3000 orally; 624, 663 i.p.; >1500, >1500 s.c. (Clark) |
Introduction
Pharmacological effects: anti-tremor paralysis drugs. It enters the brain tissue through the blood-brain barrier, and is decarboxylated by dopa decarboxylase and converted into dopamine, which plays a role. It is used for primary tremor paralysis and non-drug-induced tremor paralysis syndrome. It has good effect on moderate and mild, severe or poor elderly.
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