L-Fmoc-Aspartic acid alpha-tert-butyl ester (CAS# 129460-09-9)

Fluorenylmethoxycarbonyl-aspartate-l-tert-butyl ester (Fmoc-Asp(tBu)-OH) is a commonly used protecting group for aspartic acid. The following is a description of its nature, use, formulation and safety information:

Nature:
-Chemical formula: C26H27NO6
-Molecular weight: 449.49g/mol
-Appearance: White crystalline solid
-Melting point: 205-207°C

Use:
- Fmoc-Asp(tBu)-OH is usually used in peptide synthesis in solid phase synthesis as an aspartic acid protecting group.
-It can generate peptide chains by introducing aspartic acid residues into the synthetic peptide sequence by means of solid phase synthesis.

Preparation Method:
- Fmoc-Asp(tBu)-OH can be obtained by reacting isopropyl acetate or sodium hydroxide with Fmoc-Asp(tBu)-OH.

Safety Information:
- Fmoc-Asp(tBu)-OH is widely used in industry and laboratories, and is generally considered to be a relatively safe substance.
-but still need to pay attention to its toxicity and irritation.
-When handling it, wear appropriate protective equipment, such as gloves and goggles, to prevent contact with skin or eyes.
-When storing and handling, it is recommended to keep it in a dry, cool place, away from fire and oxidizing agents.

Please note that the safety of chemicals needs to be treated with caution. Experiments should be carried out in accordance with safe operating guidelines and waste disposal in accordance with relevant regulations.