isosorbide dinitrate（CAS#87-33-2）
| Hazard Symbols | Xn – Harmful |
| Risk Codes | R5 – Heating may cause an explosion R22 – Harmful if swallowed |
| Safety Description | 36 – Wear suitable protective clothing. |
| UN IDs | UN 2907 |
| HS Code | 2932999000 |
| Hazard Class | 4.1 |
| Packing Group | II |
| Toxicity | LD50 oral in rat: 747mg/kg |
Introduction
Isosorbide dinitrate. The following is an introduction to the properties, uses, preparation methods and safety information of isosorbide nitrate:
1. Nature:
- Appearance: Isosorbide dinitrate is usually a colorless to pale yellow liquid.
- Smell: Has a pungent taste.
- Solubility: Soluble in water and organic solvents, such as ethanol, ether, etc.
2. Usage:
- Isosorbide nitrate is mainly used in the preparation of explosives and gunpowder. As an energetic substance with a high nitrogen content, it is widely used in military and civilian fields.
- Isosorbide nitrate can also be used as a nitrification agent in organic synthesis.
3. Method:
- Preparation of isosorbide nitrate is usually obtained by oxidation of isosorbate (e.g., isosorbide acetate). The oxidizing agent can be high concentrations of nitric acid or lead nitrate, etc.
4. Safety Information:
- Isosorbide nitrate is an explosive substance that is highly hazardous. It should be stored in a fire-proof, explosion-proof and well-sealed container, away from fire and heat sources.
- Appropriate safety measures must be taken when carrying, storing, and handling isosorbide dinitrate, including wearing protective eyewear, gloves, and gowns, ensuring good ventilation, and avoiding inhalation or contact.
- When handling isosorbide nitrate, the relevant safety operating procedures should be followed and the provisions of laws and regulations should be followed.
