ibrutinib N-1(CAS#1022150-12-4)

Introduction

The following is an introduction to the properties, uses, preparation methods and safety information of ibrutinib intermediates:Properties: Ibrutinib intermediate is a white solid with benzene ring and styrene ring in its chemical structure. It is an intermediate product in the synthesis of ibrutinib and contains a deethoxy benzene ring in its chemical structure.Uses: Ibrutinib intermediates are used as synthetic raw materials for ibrutinib. Ibrutinib is a tyrosine kinase inhibitor widely used in the treatment of chronic myeloid leukemia and kodakin leukemia.Preparation method: The preparation of ibrutinib intermediates usually includes the following steps: the conversion of imatinib in the gas phase into ibrutinib intermediates through oxidation reaction. Then, pure ibrutinib intermediate products are obtained through steps such as crystallization and purification.It can cause irritation to the eyes, skin, and respiratory system, and should be used with appropriate protective equipment such as chemical gloves and protective eyewear. Ibrutinib intermediates should be kept dry and protected from light, avoiding contact with oxidants and strong acids. When handling ibrutinib intermediates, the relevant safety operating procedures should be strictly followed.