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GS-5817 interMediate(CAS#334769-80-1)

Chemical Property:

Molecular Formula C11H19NO4
Molar Mass 229.27
Density 1.150
Boling Point 343.2±35.0 °C(Predicted)
pKa 4.02±0.40(Predicted)
Storage Condition 2-8°C
Refractive Index 1.49

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Introduction

(2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid is an organic compound, also known as (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid. The following is a description of some of the properties, uses, preparation and safety information of the compound:

 

Nature:

-Appearance: White crystalline solid

-molecular formula: C11H19NO4

-Molecular weight: 233.27g/mol

-Melting Point: 75-77 ℃

-Solubility: Soluble in common organic solvents such as ethanol, chloroform, dichloromethane

 

Use:

- (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid is usually used as a reagent for C- C bond formation reactions in organic synthesis, and has a catalytic effect.

-can be applied to the pharmaceutical field of drug development and synthesis.

-can be used to synthesize other organic compounds.

 

Method:

A commonly used method for preparing (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid is to first use 5-methylpyrrolidine and N-tert-butoxycarbonyl-α-chloroacetamide as raw materials, the target product was synthesized under alkaline conditions.

 

Safety Information:

- (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid is generally relatively safe under regular operating conditions, but the following matters still need to be paid attention:

-Avoid inhalation, contact with skin and eyes.

-Wear protective glasses and gloves during operation.

-Maintain good ventilation during operation.

-In case of contact, rinse immediately with plenty of water.

-Waste disposal is subject to local regulations.


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