GS-5817 interMediate(CAS#334769-80-1)
Introduction
(2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid is an organic compound, also known as (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid. The following is a description of some of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White crystalline solid
-molecular formula: C11H19NO4
-Molecular weight: 233.27g/mol
-Melting Point: 75-77 ℃
-Solubility: Soluble in common organic solvents such as ethanol, chloroform, dichloromethane
Use:
- (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid is usually used as a reagent for C- C bond formation reactions in organic synthesis, and has a catalytic effect.
-can be applied to the pharmaceutical field of drug development and synthesis.
-can be used to synthesize other organic compounds.
Method:
A commonly used method for preparing (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid is to first use 5-methylpyrrolidine and N-tert-butoxycarbonyl-α-chloroacetamide as raw materials, the target product was synthesized under alkaline conditions.
Safety Information:
- (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid is generally relatively safe under regular operating conditions, but the following matters still need to be paid attention:
-Avoid inhalation, contact with skin and eyes.
-Wear protective glasses and gloves during operation.
-Maintain good ventilation during operation.
-In case of contact, rinse immediately with plenty of water.
-Waste disposal is subject to local regulations.