page_banner

product

FMOC-O-tert-Butyl-L-threonine(CAS# 71989-35-0)

Chemical Property:

Molecular Formula C23H27NO5
Molar Mass 397.46
Density 1.2197 (rough estimate)
Melting Point 131-134°C
Boling Point 520.91°C (rough estimate)
Specific Rotation(α) 40 º (c=1, chloroform)
Flash Point 305.6°C
Solubility almost transparency in Ethylacetate
Vapor Presure 2.24E-14mmHg at 25°C
Appearance White to Light Yellow Crystal
Color White
BRN 4581133
pKa 3.42±0.10(Predicted)
Storage Condition 2-8°C
Refractive Index 15 ° (C=1, AcOEt)
MDL MFCD00077075
Physical and Chemical Properties White crystalline powder; Insoluble in water and petroleum ether, soluble in ethyl acetate and DMF;mp is 129-132 ℃; Specific optical rotation [α]20D 15.5 °(0.5-2.0 mg/ml, ethyl acetate),[Α] 20D-4.5 °(0.5-2.0 mg/ml,DMF).

Product Detail

Product Tags

Risk Codes R36/37/38 – Irritating to eyes, respiratory system and skin.
R50/53 – Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Description S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S27 – Take off immediately all contaminated clothing.
S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S61 – Avoid release to the environment. Refer to special instructions / safety data sheets.
S60 – This material and its container must be disposed of as hazardous waste.
S29/56 -
UN IDs 3077
WGK Germany 3
HS Code 29242990

 

Introduction

FMOC-O-tert-butyl-L-threonine is a compound with the following properties:

 

Appearance: White or off-white crystalline solid.

Solubility: soluble in organic solvents, such as dimethyl sulfoxide, N,N-dimethylformamide, etc., insoluble in water.

 

Use of FMOC-O-tert-butyl-L-threonine:

Peptide synthesis: as a protective group, it is used for the synthesis of peptide sequences and ion exchange reactions within them.

Biochemical research: for the synthesis and study of natural peptides and proteins.

 

Preparation method of FMOC-O-tert-butyl-L-threonine:

FMOC-O-tert-butyl-L-threonine can be synthesized by the following steps:

L-threonine is reacted with FMOC-O-tert-butyl-N-hydroimide to generate FMOC-O-tert-butyl-L-threonine-N-agar powder ester.

FMOC-O-tert-butyl-L-threonine-N-agar powder ester was hydrolyzed to obtain FMOC-O-tert-butyl-L-threonine.

 

Safety information of FMOC-O-tert-butyl-L-threonine:

Avoid direct contact with the skin and eyes, irritation and allergic reactions may occur.

Please operate in a well-ventilated place and avoid inhaling vapors or dust.

It should be sealed tightly sealed when storing and avoid contact with oxidants.

Use personal protective measures such as protective gloves, glasses, and lab coats during use.


  • Previous:
  • Next:

  • Write your message here and send it to us