FMOC-NLE-OH （CAS# 77284-32-3)
| Safety Description | S22 – Do not breathe dust. S24/25 – Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 2924 29 70 |
| Hazard Class | IRRITANT |
Introduction
N-Fmoc-L-norleucine (Fmoc-L-Norleucine) is an amino acid derivative. It has the following properties:
1. Appearance: Fmoc-L-norleucine is a white to yellowish solid.
2. Solubility: It dissolves well in some organic solvents (such as methanol, dichloromethane and dimethylthionamide).
3. Stability: The compound can be stored stably for a long time at room temperature.
Fmoc-L-norleucine has many applications in biochemistry and organic synthesis:
1. Peptide synthesis: It is often used in solid phase synthesis and liquid phase synthesis as one of the amino acid units for constructing polypeptide chains.
2. protein research: Fmoc-L-norleucine can be used to study protein structure and function, and related genetic engineering research.
3. Drug development: The compound can be used as a starting material for the design and synthesis of drug candidates.
The preparation method of Fmoc-L-norleucine is generally realized by organic synthesis. A common synthetic route is the reaction of norleucine with Fmoc-carbamate under basic conditions.
Regarding safety information, Fmoc-L-norleucine is relatively safe under general operating conditions, but the following matters still need to be noted:
1. Avoid contact with skin and eyes: Wear appropriate personal protective equipment, such as lab gloves and goggles.
2. Avoid inhalation or ingestion: Good ventilation should be ensured during operation to avoid dust generation. If inhaled or ingested, seek medical attention immediately.
3. storage and handling: Fmoc-L-norleucine should be stored in a dry, cool place, away from combustibles. Disposal of waste shall comply with relevant environmental regulations.
