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Fmoc-N-trityl-L-asparagine (CAS# 132388-59-1)

Chemical Property:

Molecular Formula C38H32N2O5
Molar Mass 596.67
Density 1.271±0.06 g/cm3(Predicted)
Melting Point 201-204°C(lit.)
Boling Point 858.1±65.0 °C(Predicted)
Specific Rotation(α) -16 º (c=1, MeOH)
Flash Point 472.8°C
Vapor Presure 2.26E-31mmHg at 25°C
Appearance White crystalline powder
Color White to Almost white
BRN 4343823
pKa 3.79±0.10(Predicted)
Storage Condition 2-8°C
Refractive Index -19 ° (C=1, DMF)
MDL MFCD00077049

Product Detail

Product Tags

Risk and Safety

Risk Codes 53 – May cause long-term adverse effects in the aquatic environment
Safety Description S24/25 – Avoid contact with skin and eyes.
S61 – Avoid release to the environment. Refer to special instructions / safety data sheets.
UN IDs UN 3077 9 / PGIII
WGK Germany 2
FLUKA BRAND F CODES 3-10
HS Code 2924 29 70
Hazard Class IRRITANT
Toxicity LD50 orally in Rabbit: > 2000 mg/kg

 Introduction

FMOC-Nγ-trityl-L-asparagine is an organic compound with the following properties:1. Appearance: FMOC-Nγ-trityl-L-asparagine is a white crystalline solid.

2. Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) and dichloromethane.

3. Stability: relatively stable at room temperature.

The main uses of FMOC-Nγ-trityl-L-asparagine are as follows:

1. Fluorescent dye: It can be used as a fluorescent probe for biochemical research and analysis.

2. peptide synthesis: it can be used as a protecting group in peptide synthesis, by introducing FMOC group at the amino end to protect other amino or hydroxyl groups to prevent unnecessary reactions.

FMOC-Nγ-trityl-L-asparagine is prepared as follows:

In general, FMOC-Nγ-trityl-L-asparagine can be prepared by reacting N-trityl-L-asparagine with FMOC acid chloride.

Regarding safety information, you need to pay attention to the following:

1. Protective measures: When handling and using the compound, you must wear appropriate personal protective equipment, such as laboratory gloves, protective glasses and laboratory clothing.

2. toxicity: FMOC-Nγ-trityl-L-asparagine may have certain toxicity to human body, so it should be used with caution, avoid inhalation, intake or contact with skin.

3. environmental impact: should comply with the relevant environmental laws and regulations, the proper disposal of waste, to avoid pollution to the environment.


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