Fmoc-L-Serine（CAS# 73724-45-5)
| Hazard Symbols | Xi – Irritant |
| Risk Codes | 36/37/38 – Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 – Do not breathe dust. S24/25 – Avoid contact with skin and eyes. S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| HS Code | 29242990 |
Introduction
N-Fmoc-L-Serine (Fmoc-L-Serine) is an organic compound commonly used in peptide synthesis. The following is a description of the properties, uses, preparation and safety information of N-Fmoc-L-serine:
Nature:
-Appearance: A white to off-white granular or crystalline powder.
-Molecular formula: C21H21NO5
-Molecular weight: 371.40g/mol
-Melting point: about 100-110 degrees Celsius
Use:
- Fmoc-L-serine is a commonly used serine derivative, which can be used in solid phase synthesis or liquid phase synthesis in the field of peptide synthesis.
-It can be used as a protecting group for serine residues to protect the hydroxyl group of serine to prevent unwanted reactions.
-In the synthesis of polypeptides and proteins, Fmoc-L-serine can be used to construct complex peptide chain structures, including modification and regulation of activity.
Preparation Method:
-The preparation of Fmoc-L-serine can be obtained by synthetic chemical methods. In general, L-serine is first reacted with Fmoc-Cl(Fmoc chloride) to form N-Fmoc-L-serine under basic conditions.
Safety Information:
- Fmoc-L-Serine is a chemical and should be handled in accordance with laboratory safety procedures.
-Avoid direct contact with skin and eyes during operation to avoid irritation.
-When storing, keep Fmoc-L-serine in a dry, cool place, away from fire and oxidizing agents.
