FMOC-L-Leucine（CAS# 35661-60-0)
| Hazard Symbols | Xi – Irritant |
| Risk Codes | 36/37/38 – Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 – Do not breathe dust. S24/25 – Avoid contact with skin and eyes. S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. S27 – Take off immediately all contaminated clothing. S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| HS Code | 2924 29 70 |
Introduction
FMOC-L-leucine is an organic compound.
Quality:
FMOC-L-leucine is a white to yellowish crystal with strong hygroscopicity. It is soluble in organic solvents such as ethanol, methanol, and dimethylformamide, among others.
Use:
FMOC-L-leucine is mainly used for peptide synthesis and polymer synthesis in solid-phase synthesis. As a protecting group in peptide synthesis, it prevents non-specific reactions of other amino acids, making the synthesis process more specific and of high purity.
Method:
FMOC-L-leucine can be prepared by condensation of leucine with 9-fluhantadone. N-acetone and leucine were added to a polar solvent, and then 9-fluhantadone was slowly added dropwise, and finally crystallization was carried out to obtain the product.
Safety Information:
FMOC-L-leucine is generally non-toxic to humans and the environment. As an organic compound, it may have an irritating effect on the skin, eyes, and mucous membranes. Prolonged contact with the skin should be avoided during use, and care should be taken to avoid contact with the eyes and inhalation of its dust.
