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FMOC-L-Isoleucine(CAS# 71989-23-6)

Chemical Property:

Molecular Formula C21H23NO4
Molar Mass 353.41
Density 1.2107 (rough estimate)
Melting Point 145-147°C(lit.)
Boling Point 486.83°C (rough estimate)
Specific Rotation(α) -12 º (c=1,DMF)
Flash Point 292.4°C
Solubility Soluble in methanol (very faint turbidity).
Vapor Presure 2.28E-13mmHg at 25°C
Appearance White fine crystal
Color White
BRN 4716717
pKa 3.92±0.22(Predicted)
Storage Condition 2-8°C
Refractive Index -12 ° (C=1, DMF)
MDL MFCD00037125
Use Used for biochemical reagents, peptide synthesis.

Product Detail

Product Tags

Hazard Symbols Xi – Irritant
Risk Codes 36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S27 – Take off immediately all contaminated clothing.
S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 3
HS Code 2924 29 70
Hazard Note Irritant

 

Introduction

Fmoc-L-isoleucine is a derivative of a natural amino acid with the following properties:

 

Appearance: generally white or off-white crystalline powder.

 

Solubility: Fmoc-L-isoleucine is soluble in organic solvents such as dimethyl sulfoxide or dimethylformamide, insoluble in water.

 

Uses: Fmoc-L-isoleucine is widely used in solid-phase synthesis and can be used for peptide synthesis and protein mass spectrometry.

 

Method: The preparation of Fmoc-L-isoleucine is usually carried out by chemical synthesis method, where the key step involves the introduction of the Fmoc protective group to the amino group of L-isoleucine.

 

Safety Information: Fmoc-L-isoleucine has no obvious toxicity and hazard under normal use conditions. Like most chemical agents, care should be taken to avoid direct contact with the skin and inhalation. Wear appropriate protective equipment, such as lab gloves and protective glasses, when using them.


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