Fmoc-L-beta-homoalanine （CAS# 193954-26-6)
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
Introduction
fmoc-L-beta-homoalanine is an organic compound commonly abbreviated as Fmoc-L-β-Ala-oh. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystal or crystalline powder
-Solubility: Soluble in most organic solvents such as dimethyl sulfoxide, dimethyl formamide and acetonitrile
-Melting Point: about 170-175 ° C
Use:
-Fmoc-L-β-Ala-Oh is a commonly used protecting group in solid phase synthesis. Since the FMOC group is easily removed under alkaline conditions, the peptide chain can be synthesized by deprotecting the group.
-It can also be used as an important raw material in the field of research biology and medicine, used in peptide drugs and organic synthesis.
-In addition, it can also be used as a starting material for peptide synthesis.
Method:
The general method for manufacturing Fmoc-L-β-Ala-Oh is as follows:
1. First, the intermediates of 9-fluorenemethanol (Fmoc-OH) and L-β-phenylalanine (β-Ala-oh) are synthesized through organic chemical synthesis.
2. Then, the intermediate is reacted to generate the final product Fmoc-L-β-Ala-oh.
Safety Information:
Fmoc-L-β-Ala-Oh is relatively safe to use under normal conditions. However, as an organic compound, it has a certain potential danger.
-Note that inhalation of dust, contact with skin and eyes should be avoided. Wear appropriate protective gloves, glasses and masks during operation.
-In case of inhalation, skin contact or eye contact, rinse immediately with water and seek medical assistance if necessary.
