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Fmoc-D-phenylalanine(CAS# 86123-10-6)

Chemical Property:

Molecular Formula C24H21NO4
Molar Mass 387.43
Density 1.276±0.06 g/cm3(Predicted)
Melting Point 181-185°C
Boling Point 620.1±50.0 °C(Predicted)
Specific Rotation(α) 38 ° (C=1, DMF)
Flash Point 328.8°C
Vapor Presure 3.07E-16mmHg at 25°C
Appearance Crystallization
Color White
BRN 4767931
pKa 3.77±0.10(Predicted)
Storage Condition 2-8°C
Refractive Index 38 ° (C=1, DMF)
MDL MFCD00062955

Product Detail

Product Tags

Safety Description S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
WGK Germany 3
FLUKA BRAND F CODES 10-21
HS Code 29242990

 

Introduction

Fmoc-D-phenylalanine is a compound that has the following properties:

 

1. Appearance: white solid

 

Fmoc-D-phenylalanine is commonly used as a protective group in peptide synthesis. It can be obtained by a protective reaction of D-phenylalanine. The specific preparation method is as follows: firstly, D-phenylalanine is reacted with fluoroformic acid at room temperature, then Fmoc-OSu is added as an esterification reagent for esterification reaction, and finally refined by some specific solvents and co-solvents.

 

Fmoc-D-phenylalanine is widely used in peptide synthesis, especially in solid-phase synthesis. It acts as a protective group for amino acids to protect other reactive groups such as amines and hydroxyl groups. Selective synthesis of peptides can be achieved by controlling the addition and removal of protecting groups.

 

1. Please follow the laboratory safety procedures and wear appropriate personal protective equipment such as gloves, goggles, etc.

2. Avoid inhaling dust or gases from the compound and avoid contact with skin and eyes.

3. During use, avoid contact with strong oxidants and strong acids.

4. In case of accidental contact, rinse immediately with plenty of water and seek medical treatment if necessary.

 


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