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Exenatide acetate(CAS#141732-76-5)

Chemical Property:

Molecular Formula C186H286N50O62S
Molar Mass 4244.60796
Melting Point >209°C (dec.)
Solubility Acetonitrile (Slightly), Water (Slightly)
Appearance Solid
Color White to Off-White
Storage Condition Refrigerator, under inert atmosphere
Physical and Chemical Properties White powder, soluble in methanol, ethanol, DMSO and other organic solvents.
Use Treatment of type 2 diabetes mellitus
Anti-HIV drugs
In vitro study A cell-cell fusion assay reveals that the effective concentration for achieving 50% inhibition (IC 50 ) of Enfuvirtide is 23 ± 6 nM. IFN-λs (1, 2, or 3) or the antiretrovirals (AZT, Efavirenz, Indinavir, and Enfuvirtide) significantly inhibita the expression of HIV p24 antigen and Gag gene in macrophages. IFN-λs (1, 2, or 3) also enhanced the anti-HIV (Bal) effect of AZT, Efavirenz, Indinavir, and Enfuvirtide.
In vivo study Enfuvirtide has a T 1/2 of 3.8 h.

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Introduction

Quality:- Appearance: Exenatide acetate is a white crystalline powder.- Solubility: It has a high solubility in water.- Stability: It is relatively stable at room temperature, but may decompose at high temperatures.Uses: Exenatide is a specific peptide growth factor that may have the effect of promoting skin cell regeneration and repair.Method:The preparation methods of exenatide acetate mainly include chemical synthesis and biotechnology methods, and the specific steps are somewhat complex and need to be carried out in chemical laboratories or industrial production.Safety Information:- Exenatide acetate is generally considered to be a relatively safe substance, but the following should be noted:- In case of contact with eyes, immediately rinse with plenty of water for at least 15 minutes and seek medical help.- Before using the substance, refer to the relevant safety data sheets and ensure that the operation is carried out in a well-ventilated environment.


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