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ethyl 5-methoxy-1-benzofuran-2-carboxylate(CAS# 50551-56-9)

Chemical Property:

Molecular Formula C12H12O4
Molar Mass 220.22
Density 1.192±0.06 g/cm3(Predicted)
Melting Point 59 °C
Boling Point 316.2±22.0 °C(Predicted)
Flash Point 145°C
Vapor Presure 0.000418mmHg at 25°C
Storage Condition 2-8℃
Refractive Index 1.557

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Introduction

Ethyl is an organic compound. The following is a description of its nature, use, preparation and safety information:

 

Nature:

-Appearance: colorless liquid

-Molecular formula: C13H12O4

-Molecular Weight: 232.23

-melting point: 37-39 ℃

-boiling point: 344-346 ℃

-Solubility: Soluble in organic solvents such as chloroform, ethanol and dichloromethane, slightly soluble in water.

 

Use:

- ethyl l is a commonly used organic synthesis intermediate that can be used to synthesize drugs, hormones and natural products.

-It can also be used as a reference substance in the field of pharmaceutical research and drug synthesis.

 

Preparation Method:

ethyl is usually synthesized by the following steps:

1. First, the methoxybenzofuran is substituted with bromoacetic acid to obtain 5-methoxybenzofuran -2-acetic acid.

2. Then, 5-methoxybenzofuran-2-acetic acid is reacted with thionyl chloride (SOCl2) to convert it into acid chloride.

3. Finally, the acid chloride is reacted with ethanol to generate ethyl phenyl.

 

Safety Information:

- ethyl l is a chemical that requires careful storage and handling.

-It is irritating and should avoid contact with skin and eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical help.

-In use, should maintain good ventilation conditions, avoid inhalation of gas and vapor.


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