ethyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylate(CAS#144927-57-1)
ethyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylate(CAS#144927-57-1)
Uses: It is an important intermediate in organic synthesis and has potential applications in the field of medicinal chemistry. It may be used to synthesize biologically active pyrrolopyrimidine drug molecules, and the chlorine atoms, ester groups and pyrrolopyrimidine rings in their structures can be modified by various chemical reactions, so as to introduce different pharmacophores to obtain compounds with specific pharmacological effects, such as drugs with antibacterial, antiviral, antitumor and other activities.
Synthesis method: Diethyl malonate is usually used as the starting material, and is synthesized through multi-step reaction. For example, diethyl malonate is first condensed with the corresponding nitrogen-containing heterocyclic compounds, and then the target product is obtained through chlorination, cyclization and other steps. However, the specific synthesis route may vary depending on the raw material and reaction conditions.