Ethyl 4 4-difluorovalerate（CAS# 659-72-3)

Introduction

Ethyl 4,4-difluoropentanoate, chemical formula C6H8F2O2, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:

-Appearance: colorless liquid

-Molecular weight: 146.12g/mol

-Boiling Point: 142-143°C

-Density: 1.119 g/mL

-Solubility: Soluble in organic solvents, insoluble in water

-Stability: stable, but susceptible to light, heat, oxidants and acids

Use:

-Ethyl 4,4-difluoropentanoate is an important organic synthesis intermediate, which has a wide range of applications in the fields of medicine, pesticide and dye industry. It can be used as a precursor for the synthesis of pharmaceuticals, pesticides and dyes, as well as for the preparation of other organic compounds.

- 4,4-difluoropentanoic acid ethyl ester can be used as solvent, esterification reagent and catalyst in organic synthesis.

Preparation Method:

The preparation of ethyl 4,4-difluoropentanoate is generally carried out by the following steps:

1. First, pentanoic acid is reacted with sulfur difluoride to obtain 4,4-difluoropentanoic acid.

2.4,4-difluoropentanoic acid is then reacted with ethanol under acidic conditions to generate ethyl 4,4-difluoropentanoate.

Safety Information:

- 4,4-difluoropentanoic acid ethyl ester is a flammable liquid, storage and operation should pay attention to avoid fire and open flame.

-use should wear protective glasses and gloves, avoid contact with the skin and inhalation of its vapor.

-Operate in a well-ventilated area to avoid entering the respiratory system.

-If accidentally touched or taken by mistake, rinse immediately with plenty of water and seek medical attention immediately.